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BDK CNS #2-3

Basic Drug Knowledge Central Nervous System Page #2-3

Generic NameBrand NameClassificationPharmacologic CategoryCommon IndicationsKey Side EffectsUS Boxed WarningsOther Notes
Dexmethylphenidate (PO) Focalin, Focalin XR CS-II CNS (Central Nervous System) Stimulant Attention-Deficit/Hyperactivity Disorder (ADHD) Insomnia, Headache, Anxiety, Weight Loss, Decreased Appetite, Hypertension High Potential for Abuse CI within 14 days of MAOI
Dextroamphetamine & Amphetamine (PO) Adderall, Adderall XR CS-II CNS (Central Nervous System) Stimulant Attention-Deficit/Hyperactivity Disorder (ADHD), Narcolepsy Insomnia, Headache, Anxiety, Weight Loss, Decreased Appetite, Hypertension High Potential for Abuse CI within 14 days of MAOI
Lisdexamfetamine (PO) Vyvanse CS-II CNS (Central Nervous System) Stimulant Attention-Deficit/Hyperactivity Disorder (ADHD) Insomnia, Headache, Anxiety, Weight Loss, Decreased Appetite, Hypertension High Potential for Abuse CI within 14 days of MAOI
Methylphenidate (PO, Transdermal) PO: Concerta, Ritalin Patch: Daytrana CS-II CNS (Central Nervous System) Stimulant Attention-Deficit/Hyperactivity Disorder (ADHD), Narcolepsy Insomnia, Headache, Anxiety, Weight Loss, Decreased Appetite, Hypertension High Potential for Abuse CI within 14 days of MAOI
Guanfacine (PO) Intuniv Selective Alpha 2A Agonist Attention-Deficit/Hyperactivity Disorder (ADHD), Hypertension (HTN) Bradycardia, Hypotension, Sedation, Skin Rash, Xerostomia, Constipation Do Not Abruptly Discontinue
Pramipexole (PO) Mirapex Dopamine Agonist Parkinson's Disease, Restless Legs Syndrome (RLS) Nausea, Hallucinations, Dizziness, Drowsiness, Compulsive Behaviors, Orthostasis
Ropinirole (PO) Requip Dopamine Agonist Parkinson's Disease, Restless Legs Syndrome (RLS) Nausea, Hallucinations, Dizziness, Drowsiness, Compulsive Behaviors, Orthostasis
Carbidopa & Levodopa (PO) Sinemet, Sinemet CR Decarboxylase Inhibitor (Carbidopa), Dopamine Precursor (Levodopa) Parkinson's Disease Nausea, orthostatic Hypotension, Dyskinesias CI within 14 days of MAOI, CI in narrow-angle glaucoma; Do Not Abruptly Discontinue
Memantine (PO) Namenda N-Methyl D-Aspartate (NMDA) Antagonist Dementia Constipation, Confusion, Dizziness, Headache
Donepezil (PO, Transdermal) PO: Aricept Transdermal: Adlarity Cholinesterase Inhibitor Dementia Nausea, Vomiting, Diarrhea
Lithium (PO) Lithobid Antimanic Agent Bipolar Disorder Tremor, Acne, Hypothyroidism, Weight Gain, Polyuria, Polydipsia, GI Upset Ability to Promptly Monitor Levels Is Necessary Narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; Therapeutic drug monitoring is recommended); Avoid in Pregnancy
Sumatriptan (PO, Intranasal, SQ) Imitrex Antimigraine Migraine Fatigue, Somnolence, Dizziness, Chest Tightness, Paresthesias CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension
Rizatriptan (PO) Maxalt Antimigraine Migraine Fatigue, Somnolence, Dizziness, Chest Tightness, Paresthesias CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension
Haloperidol (PO, IV, IM) Haldol First-Generation Antipsychotic Schizophrenia Sedation, EPS, Parkinsonism, Xerostomia, Orthostatic Hypotension, Weight Gain, QTc Prolongation Elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Clozapine (PO) Clozaril Second-Generation Antipsychotic Treatment-Resistant Schizophrenia Sedation, Constipation, Orthostatic Hypotension, Sialorrhea, Hyperglycemia, Weight Gain, Neutropenia May cause severe neutropenia; May cause fatal orthostatic hypotension, bradycardia, & syncope; May cause seizures, fatal myocarditis & cardiomyopathy; Elderly patients w/ dementia-related psychosis treated w/ antipsychotic draws at increased risk of death
Aripiprazole (PO, IM) PO/IM: Abilify IM: Aristada Second-Generation Antipsychotic Schizophrenia, Bipolar Disorder, Major Depressive Disorder [(MDD) Adjunct to Antidepressants] Akathisia, Restlessness, Sedation, EPS, Constipation, Orthostatic Hypotension, Weight Gain Antidepressants increase the risk of suicidal thinking & behavior in children, adolescents & young adults; Elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Quetiapine (PO) Seroquel, Seroquel XR Second-Generation Antipsychotic Schizophrenia, Bipolar Disorder, Major Depressive Disorder [(MDD) Adjunct to Antidepressants] Sedation, EPS, Constipation, Orthostatic Hypotension, Weight Gain Antidepressants increase the risk of suicidal thinking & behavior in children, adolescents & young adults; Elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Lurasidone (PO) Latuda Second-Generation Antipsychotic Schizophrenia, Bipolar Disorder, Major Depressive Disorder [(MDD) Adjunct to Antidepressants] Sedation, EPS, Constipation, Orthostatic Hypotension, Weight Gain Antidepressants increase teh risk of suicidal thinking & behavior in children, adolescents & young adults; Elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death CI with strong #a4 inhibitors & inducers
Olanzapine (PO, IM) Zyprexa Second-Generation Antipsychotic Schizophrenia, Bipolar Disorder, Major Depressive Disorder [(MDD) Adjunct to Antidepressants]
Risperidone (PO, IM) PO: Risperdal IM: Risperdal Consta Second-Generation Antipsychotic Schizophrenia
Created by: nataliemvo
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