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ISAT Exam 1
| Question | Answer |
|---|---|
| What are the set backs to vaccine development? | Too advanced disease stage, tumor highly heterogenous, prior treatment (chemotherapy), rapid and unpredictable, uncertain correlation between trials and success |
| What are the vaccines for treatment of cancer? | Tumor cell vaccine Antigen vaccine Dendritic cell vaccine Anti-Idiotype vaccine DNA vaccine Vector Based vaccine |
| Tumor cell vaccine | Cancer cells cause T cells to react Autologous- killed tumor cells from patient Allogenic- from other patient, stock cells |
| Antigen vaccine | use antigens/peptides |
| Anti-idiotype vaccine | idiotype used to produce Ab from B cells (plasma cells) Promising for lymphomas |
| DNA vaccines | cells injected by foreign DNA codes for foreign protein antigens remove patient's cells, alter code, and return |
| Vector Based vaccine | combined technique deliver more than one cancer antigen at one time |