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Top drug list F25
| Question | Answer |
|---|---|
| Zestril | Lisinopril, ACE, Inhibits angiotensin 1 to 2 |
| Norvasc, norliqva, katerzia | Amlodipine, Ca Ch Bl |
| Cozaar | Losartan, ARB, Blocks angiotensin two recenter, prevents vasoconstriction |
| Microzide, Aquazide H, Hydrodiuril | Hydrochlorothiazide |
| Lasix | Furosemide, Loop diuretic, Inhibits sodium and cl uptake in distal renal tubules and ascending loop of henle |
| Tenormin | Atenolol |
| Coreg | Carvedilol, B and a blocker |
| Inderal | Propranolol |
| Procardia | Nifedipine Ca ch bl |
| Apresoline | Hydralazine Vasodilator Relaxes anterior smooth muscle |
| Diovan | Valsartan |
| Benicar | Olmesartan |
| Vasotec | Enalapril |
| Catapres | Clonidine Alpha 2 adrenergic agonist Stimulates receptors in brain stem, reduce sympathetic outflow and lowering blood pressure |
| Cardizem | Diltiazem Ca Ch Bl Non dihydropyradine |
| Calan, verelan | Verapamil Ca ch bl Non dihydropyradine |
| Lopressor. Tartrate Toprol XL. succinate | Metoprolol |
| Hemiclor Thalitone | Chlorthalidone Thiazide |
| Aldactone | Spironolactone K sparring diuretic and aldosterone receptor antagonist Competes with aldosterone in distal renal tubules, increasing Na and water excretion, keeping K and H |
| Cardicor | Bisoprolol |
| Zocor | Simvastatin |
| Coumadin, Jantoven | Warfarin Vitamin K antag, Inhibits synthesis of clotting factors 2,7,9,10 |
| Crestor | Rosuvastatin |
| Lipitor | Atorvastatin |
| Pravachol | Pravastatin |
| Tricor | Fenofibrate Fabric acid derivative Activate PPAR-a, increases lipolysis and eliminates triglycerides |
| Niaspan (DSC) Niacor | Niacin Nicotinic acid Inhibits lipolysis in fat tissue, reduces VLDL and increases HDL |
| Leqvio | Inclisiran siRNA agent |
| Lovaza | Omega 3 acid ethyl esters Reduces hepatic triglyceride synthesis and increases lipase |
| Zetia | Ezetimibe Cholesterol adsorption inh Inhibits chol ads at brush border of small intestine |
| Repatha | Evolocumab PCSK9 inh |
| Praluent | Alirocumab PCSK9 inh |
| Crestor | Rosuvastatin |
| Leqvio | Inclisiran siRNA agent |
| Xarelto | Rivaroxaban Direct factor Xa antagonist Inhibits factor Xa, prevents prothrombin to thrombin |
| Eliquis | Apixaban Direct Xa factor antagonist |
| Hep-lock | Heparin Anticoagulant Enhances anti thrombin 3, inhibits thrombin and Xa factor |
| Lovenox | Enoxaparin Low molecular weight heparin |
| Nexterone,pacerone | Amiodarone Class 3 antiarrhythmic Inh K channels that repolarize cardiac cell membr, prolongs action potential and refractory period of cardiac cells |
| Betapace | Sotalol Class 3 antiarrhythmic Non selectively blocks B receptors and K channels |
| Xylocaine | Lidocaine Local anesthetic: class 1b antiarrhythmic Inh Na channels, inhibits nerve impulse |
| Lanoxin | Digoxin Cardiac glycoside Affects parasympathetic, slows AV conduction, dec HR |
| Tikosyn | Dofetilide Class 3 antiarrhythmic |
| Glucophage | Metformin Biguanide Dec. hepatic gluc prod and intestine gluc abs. Inc insulin sensitivity by inc peripheral gluc uptake |
| Lantus, Basaglar, Toujeo, Semglee | Insulin Glargine long acting insulin Basal glycemic control by reg gluc metab Inc gluc uptake in muscle and fat Inh hepatic gluc prod |
| Humalog, Admelog, Lyumjev | Insulin Lispro Rapid acting insulin Bolus glycemic control by reg gluc metab Inc gluc uptake in muscle and fat Inh hep gluc prod |
| Novolog, Fiasp, Merilog | Insulin aspart Rapid acting insulin Bolus glycemic control by reg gluc metab Inc gluc uptake in muscle and fat Dec hepatic gluc prod |
| Victoza, Saxenda | Liraglutide GLP-1 receptor agonist Activates GLP-1, Inc gluc dep insulin secretion Dec inappropriate glucagon prod Dec gastric emptying and food intake |
| Ozempic, Wegovy | Semaglutide GLP-1 rec agonist Act GLP-1, Inc gluc dep insulin prod Dec inappropriate glucagon prod Dec gastric emptying and food intake |
| Trulicity | Dulaglutide GLP-1 agonist Act GLP-1, Inc gluc dep insulin prod Dec inappropriate glucagon prod Dec gastric emptying and food intake |
| Monjaro, Zepbound | Tirzepatide GIP/GLP-1 agonist Act GIP/GLP-1, inc gluc dep insulin prod, dec glucagon prod, dec food intake |
| Januvia | Sitagliptin DPP-4 inh Inh DPP-4, inc incretion and gluc dep insulin prod |
| Tradjenta | Linagliptin DPP-4 inh Inc incretion and gluc dep insulin prod |
| Actos | Pioglitazone Thiazolidinedione Inc insulin sensitivity by binding PPAR-y |
| Glucotrol XL | Glipizide Sulfonylurea Inc insulin prod in pancreatic B cells by blocking ATP dep K channels |
| Amaryl | Glimepiride Sulfonylurea Inc insulin prod in pancreatic B cells by blocking ATP K channels |
| Farxiga | Dapagliflozin SGLT2 inh Inh SGLT2 in proximal renal tubules, dec gluc reabsorption |
| Jardiance | Empagliflozin SGLT2 inh Inh SGLT2 in proximal renal tubules, Dec gluc reabs |
| Invokana | Canagliflozin SGLT2 inh Inh SGLT2 in proximal renal tubules, Dec gluc reabs |
| Neurontin | Gabapentin Anticonvulsant Reg voltage gated Ca ch. in CNS by binding a2-delta subunit and influences GABAergic activity |
| Keppra | Levetiracetam Inh voltage gated N type Ca ch., release GABA, modulates neurotransmitter release |
| Topamax, Trokendi XR | Topiramate Anticonvulsant Blocks volt. Dep Na channels, inc GABA activity, inh AMPA/kainate glutamate rec, inh carbonic anhydrate |
| Lamictal | Lamotrigine Anticonvulsant Inh voltage gated Na channels, stabilize neuronal membr and red excitatory transmitters |
| Dilantin | Phenytoin Hydantoin Anticonvulsant Stabilize neuronal membr and dec seizure act by dec influx Na in motor cortex |
| Synthroid | Levothyroxine Thyroid hormone Hypothyroidism agent Synthetic T4 converted to T3, binds to thyroid rec |
| Ambien | Zolpidem Hypnotic Inc GABA by binding BZ1 |
| Lunesta | Eszopiclone Hypnotic Interacts w GABA rec at binding domains close to benzodiazepine rec |
| Vyvanse | Lisdexamfetamine CNS stimulant Stimulant (ADHD) prodrug of dextroamphetamine, inc norepinephrine and dopamine |
| Adderall | Dextro/amphetamine CNS stimulant Stimulant (ADHD) inc dopamine and norepinephrine release in nerve terminals |
| Lexapro | Escitalopram SSRI Inh serotonin reuptake in brain |
| Zoloft | Sertraline SSRI |
| Celexa | Citalopram SSRI |
| Desyrel | Trazadone Serotonin reuptake inh/antagonist Inh serotonin reuptake and blocks histamine and a1 adrenergic receptors |
| Elavil | Amitriptyline Tricyclic antidepressant Inh norepinephrine and serotonin reuptake |
| Paxil | Paroxetine SSRI |
| Prozac | Fluoxetine SSRI |
| Remeron | Mirtazapine a2 antagonist Antidepressant Inc dopamine release by blocking a2-adrenergic and 5-HT2C receptors |
| Cymbalta | Duloxetine SNRI Inh serotonin and norepinephrine reuptake |
| Wellbutrin | Bupropion Norepinephrine-dopamine reuptake inh Antidepressant Inh dopamine and norepinephrine reuptake |
| Effexor | Venlafaxine SNRI |
| Seroquel | Quetiapine Atypical antipsychotic Antipsychotic Antag D2 and 5-HT2 rec |
| Risperdal | Risperidone Atypical antipsy Antipsychotic Antag D2 and 5-HT2 rec |
| Abilify | Aripiprazole Atypical antipsy Antipsy Agonist to D2 and 5-HT1A, Antag to 5-HT2A rec |
| Haldol | Haloperidol Typical antipsychotic (butyrophenone) Antipsychotic Nonselect. Inh D2 rec |
| Xanax | Alprazolam Benzodiazepine (anxiolytic) Benz Inc GABA by binding to its rec in CNS |
| Klonopin | Clonazepam Benz. (Anticonvulsant) Benz Inc GABA by binding it’s rec in CNS |
| Valium | Diazepam Benz (Anxiolytic) Benz Inc GABA by binding it’s rec in CNS |
| Ativan | Lorazepam Benz (anticonvulsant) Inc GABA by binding it’s rec in CNS |
| Bucapsol | Buspirone Anti anxiety Anxiolytic Unknown, high affinity for 5-HT1A and 5-HT2 w/o affecting Benz-GABA rec. |