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BDK CNS #1
Basic Drug Knowledge Central Nervous System Page #1
| Generic | Brand | Pharmacologic Category | Common Indications | Key Side Effects | US Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|
| Mirtazapine (PO) | Remeron | Alpha 2 Antagonist | Major Depressive Disorder (MDD) | Drowsiness, Weight Gain, Xerostomia, Increased Appetite, Constipation | Increased risk of suicidal thinking & behavior in children, adolescents, and young adults | |
| Bupropion (PO) | Wellbutrin SR, Wellbutrin XL | Norepinephrine-Dopamine Reuptake Inhibitor | Major Depressive Disorder (MDD) | Tachycardia, Headache, Agitation, Dizziness, Insomnia, Weight Loss, Xerostomia | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults; Serious neuropsychiatric reactions have occurred | Use may increase risk of seizures (CI in patients with seizure disorders and/or eating disorders) |
| Atomoxetine (PO) | Strattera | Selective Norepinephrine Reuptake Inhibitor | Attention-Deficit/Hyperactivity Disorder (ADHD) | Hypertension, Tachycardia, Headache, Xerostomia, Nausea, Vomiting, Constipation, Decreased Appetite, Insomnia | Increased risk of suicidal ideation in children or adolescents | CI within 14 days of MAOI |
| Desvenlafaxine (PO) | Pristiq | Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) | Major Depressive Disorder (MDD) | Headache, Xerostomia, Nausea, Vomiting, Constipation, Decreased Appetite, Insomnia, Diaphoresis, Hypertension, Sexual Dysfunction | Increased risk of suicidal thinking & behavior in children, adolescents, and young adults | CI within 14 days of MAOI; Do not discontinue abruptly |
| Duloxetine (PO) | Cymbalta | Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) | Major Depressive Disorder (MDD), Neuropathic Pain | Headache, Xerostomia, Nausea, Vomiting, Constipation, Decreased Appetite, Insomnia, Diaphoresis, Hypertension, Sexual Dysfunction | Increased risk of suicidal thinking & behavior in children, adolescents, and young adults | CI within 14 days of MAOI; Do not discontinue abruptly |
| Venlafaxine (PO) | Effexor XR | Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) | Major Depressive Disorder (MDD) | Headache, Xerostomia, Nausea, Vomiting, Constipation, Decreased Appetite, Insomnia, Diaphoresis, Hypertension, Sexual Dysfunction | Increased risk of suicidal thinking & behavior in children, adolescents, and young adults | CI within 14 days of MAOI; Do not discontinue abruptly |
| Citalopram (PO) | Celexa | Selective Serotonin Reuptake Inhibitor (SSRI) | Major Depressive Disorder (MDD) | Drowsiness, Insomnia, Nausea, Vomiting, Xerotstomia, Sexual Dysfunction, Headache, Diaphoresis | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | CI within 14 days of MAOI; Do not discontinue abruptly (All except Fluoxetine) |
| Fluoxetine (PO) | Prozac | Selective Serotonin Reuptake Inhibitor (SSRI) | Major Depressive Disorder (MDD) | Drowsiness, Insomnia, Nausea, Vomiting, Xerotstomia, Sexual Dysfunction, Headache, Diaphoresis | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | CI within 14 days of MAOI; Do not discontinue abruptly (All except Fluoxetine) |
| Escitalopram (PO) | Lexapro | Selective Serotonin Reuptake Inhibitor (SSRI) | Major Depressive Disorder (MDD) | Drowsiness, Insomnia, Nausea, Vomiting, Xerotstomia, Sexual Dysfunction, Headache, Diaphoresis | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | CI within 14 days of MAOI; Do not discontinue abruptly (All except Fluoxetine) |
| Paroxetine (PO) | Paxil | Selective Serotonin Reuptake Inhibitor (SSRI) | Major Depressive Disorder (MDD) | Drowsiness, Insomnia, Nausea, Vomiting, Xerotstomia, Sexual Dysfunction, Headache, Diaphoresis | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | CI within 14 days of MAOI; Do not discontinue abruptly (All except Fluoxetine) |
| Sertraline (PO) | Zoloft | Selective Serotonin Reuptake Inhibitor (SSRI) | Major Depressive Disorder (MDD) | Drowsiness, Insomnia, Nausea, Vomiting, Xerotstomia, Sexual Dysfunction, Headache, Diaphoresis | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | CI within 14 days of MAOI; Do not discontinue abruptly (All except Fluoxetine) |
| Trazodone (PO) | Desyrel | Serotonin Reuptake Inhibitor | Insomnia, Major Depressive Disorder (MDD) | Sedation, Headache, Dizziness, Xerostomia, Nausea, Priapism | Increased risk of suicidal thinking and behavior in children, adolescents and young adults | |
| Amitriptyline (PO) | Elavil | Tricyclic Antidepressant (TCA) | Major Depressive Disorder (MDD), Diabetic Neuropathy, Migraine Prophylaxis | Dizziness, Drowsiness, Orthostatic Hyportension, Sexual Dysfunction, Xerostomia, Blurred Vision, Constipation | Increased risk of suicidal thinking and behavior in children, adolescents and young adults | CI within 14 days of MAOI; Do Not Discontinue Abruptly |
| Nortriptyline (PO) | Pamelor | Tricyclic Antidepressant (TCA) | Major Depressive Disorder (MDD), Diabetic Neuropathy, Migraine Prophylaxis | Dizziness, Drowsiness, Orthostatic Hyportension, Sexual Dysfunction, Xerostomia, Blurred Vision, Constipation | Increased risk of suicidal thinking and behavior in children, adolescents and young adults | CI within 14 days of MAOI; Do Not Discontinue Abruptly |
| Doxepine (PO) | Silenor | Tricyclic Antidepressant (TCA) | Insomnia | Somnolence, Sedation, Nausea | Increased risk of suicidal thinking and behavior in children, adolescents, and youn adults | CI within 14 days of MAOI; Do Not Discontinue Abruptly |
Created by:
nataliemvo
Popular Pharmacology sets