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ID 2

Pharmacologic Category Generic Name Brand NameCommon Indications Essential Knowledge
Carbapenem meropenem (IV) Merrem Meningitis, HAP, DFI, IAI Activity against: Pseudomonas aeruginosa, ESBL-producing Enterobacteriaceae Key Side Effects: diarrhea, hypersensitivity reactions, seizures with excessive doses
Carbapenem ertapenem (IV) Invanz DFI, IAI Activity against: ESBL-producing Enterobacteriaceae Key Side Effects: diarrhea, hypersensitivity reactions, seizures with excessive doses
Fluoroquinolone antibiotic ciprofloxacin (PO, IV) Cipro Pyelonephritis, HAP, VAP Activity against: Pseudomonas aeruginosa, atypicals, Enterobacteriaceae Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warnings: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbat
Fluoroquinolone antibiotic levofloxacin (PO, IV) Levaquin CAP, HAP, VAP, pyelonephritis Activity against: Pseudomonas aeruginosa, Streptococcus pneumoniae, atypicals, Enterobacteriaceae Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warnings: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbat
Fluoroquinolone antibiotic moxifloxacin (ophthalmic, PO, IV) Ophthalmic: Vigamox, PO, IV: Avelox Ophthalmic: bacterial conjunctivitis, PO, IV: CAP Activity against: Streptococcus pneumoniae, atypicals, tuberculosis Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warnings: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbat
Macrolide antibiotic azithromycin (PO, IV) Zithromax, Z-Pak, Zmax CAP Activity against: Chlamydia trachomatis, atypicals Key Side Effects: diarrhea, QTc prolongation
Macrolide antibiotic fidaxomicin (PO) Dificid CDI Activity against: Clostridioides difficile Key Side Effects: nausea Other Notes: do not use for systemic infections (no systemic absorption)
Tetracycline antibiotic doxycycline (PO, IV) Vibramycin SSTI, CAP, tickborne diseases Activity against: MRSA, atypicals Key Side Effects: esophagitis (doxycycline only), photosensitivity, DILE (minocycline only) Other Notes: avoid in children <8 years old, pregnancy, and breastfeeding due to bone growth suppression and teeth discoloration; take oral tetracyclines 2 hou
Tetracycline antibiotic minocycline (PO, IV) Minocin SSTI, acne Activity against: MRSA Key Side Effects: esophagitis (doxycycline only), photosensitivity, DILE (minocycline only) Other Notes: avoid in children <8 years old, pregnancy, and breastfeeding due to bone growth suppression and teeth discoloration; take oral tetracyclines 2 hou
Created by: ATrainer23
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