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ID 4

Pharmacologic CategoryGenericBrandClassificationIndicationKey side effectsUS Boxed warningsOther Notes
Allylamine antifungal terbinafine (PO, topical) Lamisil Topical: OTC Onychomycosis nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache N/A N/A
Azole antifungal fluconazole (PO, IV) Diflucan N/A Vulvovaginal candidiasis, oropharyngeal candidiasis, invasive candidiasis nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases N/A N/A
Azole antifungal ketoconazole (PO, topical) Nizoral Topical: OTC Tinea infections nausea, abdominal pain, diarrhea, QTc prolongation, increased hepatic transaminases serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation have occurred; may cause QTc prolongation and drug interactions leading to QTc prolongation N/A
Polyene antifungal nystatin (PO) --- N/A Oropharyngeal candidiasis phlebitis, diarrhea, vomiting, anemia, fever N/A N/A
Polyene antifungal nystatin (topical) Nystop N/A Cutaneous and mucocutaneous fungal infections burning, itching N/A only use oral solutions for thrush
Echinocandin antifungal micafungin (IV) Mycamine N/A Invasive candidiasis no major side effects N/A N/A
Glucocorticoid and azole antifungal betamethasone and clotrimazole (topical) Lotrisone N/A Cutaneous fungal infections burning, itching, dryness, skin atrophy N/A do not use for diaper dermatitis; adrenal suppression with long-term use over large areas of skin
Neuraminidase inhibitor antiviral oseltamivir (PO) Tamiflu N/A Influenza nausea, vomiting, neuropsychiatric events (i.e., confusion, delirium, hallucinations) in pediatric patients (rare) N/A N/A
Antiviral acyclovir (PO, IV) Zovirax N/A Herpes simplex virus nausea, increased hepatic transaminases, crystalluria N/A vesicant
Antiviral valacyclovir (PO) Valtrex N/A Herpes simplex virus nausea, increased hepatic transaminases N/A N/A
Antiviral nirmatrelvir + ritonavir (PO) Paxlovid N/A COVID-19 diarrhea, dysgeusia significant drug interactions; strong CYP3A inhibitor N/A
Antiviral remdesivir (IV) Veklury N/A COVID-19 hyperglycemia, renal impairment N/A N/A
Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) emtricitabine + tenofovir disoproxil fumarate (PO) Truvada N/A HIV Infection, PreP, PEP decreased bone mineral density, kidney injury, nausea, diarrhea post treatment acute exacerbation of hepatitis B, risk of drug resistance with use for preexposure prophylaxis N/A
Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) and Integrase strand transfer inhibitor (INSTI) emtricitabine (NRTI) + tenofovir alafenamide (NRTI) + bictegravir (INSTI) (PO) Biktarvy N/A HIV infection increased serum bilirubin, headache, weight gain, insomnia, diarrhea, nausea post treatment acute exacerbation of hepatitis B take oral INSTIs 2 hours before or 6 hours after products containing calcium, aluminum, magnesium, or iron
Created by: ziad5
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