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ID 2

Pharmacologic CategoryGenericBrandCommon IndicationActivity AgainstKey side effectsUS Boxed WarningsOther Notes
Carbapenem Meropenem (IV) Merrem Meningitis, HAP, DFI, IAI Pseudomonas aeruginosa, ESBL-producing Enterobacteriaceae Key side effects: diarrhea, hypersensitivity reactions, seizures with excessive doses N/A N/A
Carbapenem Ertapenem (IV) Invanz DFI, IAI ESBL-producing Enterobacteriaceae Key side effects: diarrhea, hypersensitivity reactions, seizures with excessive doses N/A N/A
Fluoroquinolone Ciprofloxacin (PO, IV) Cipro Pyelonephritis, HAP, VAP Pseudomonas aeruginosa, atypical, Enterobacteriaceae Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warnings: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis Taken 2 hours prior or 6 hours after products having divalent/trivalent cations (dairy products, calcium-fortified juices, oral multivitamins, mineral supplements) increased risk of aortic dissection or rupture, dysglycemias, CNS side effects
Fluoroquinolone Levofloxacin (PO, IV) Levaquin CAP, HAP, VAP, pyelonephritis Pseudomonas aeruginosa, Streptococcus pneumoniae, atypicals, Enterobacteriaceae Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warnings: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis Taken 2 hours prior or 6 hours after products having divalent/trivalent cations (dairy products, calcium-fortified juices, oral multivitamins, mineral supplements) increased risk of aortic dissection or rupture, dysglycemias, CNS side effects
Fluoroquinolone Moxifloxacin (opthalmic, PO, IV) Ophthalmic: Vigamox, PO, IV: Avelox Ophthalmic: bacterial conjunctivitis, PO, IV: CAP Streptococcus pneumoniae, atypicals, tuberculosis Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warnings: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis Taken 2 hours prior or 6 hours after products having divalent/trivalent cations (dairy products, calcium-fortified juices, oral multivitamins, mineral supplements) increased risk of aortic dissection or rupture, dysglycemias, CNS side effects
Macrolide antibiotic Azithromycin (PO, IV) Zithromax, Z-Pak, Zmax CAP Chlamydia trachomatis, atypicals diarrhea, QTc prolongation N/A N/A
Macrolide antibiotic fidaxomicin (PO) Dificid CDI Clostridioides difficile nausea N/A do not use for systemic infections (no systemic absorption)
Tetracycline antibiotic doxycycline (PO, IV) Vibramycin SSTI, CAP, tickborne diseases MRSA, atypicals esophagitis (doxycycline only), photosensitivity, DILE (minocycline only) N/A avoid in children <8 years, pregnancy, and breastfeeding due to bone growth suppression and teeth discolor; tetracyclines 2 hrs prior or 6 hrs after items having divalent/trivalent cations
Tetracycline antibiotic minocycline (PO, IV) Minocin SSTI, acne MRSA esophagitis (doxycycline only), photosensitivity, DILE (minocycline only) N/A avoid in children <8 years, pregnancy, and breastfeeding due to bone growth suppression and teeth discolor; tetracyclines 2 hrs prior or 6 hrs after items having divalent/trivalent cations
Created by: ziad5
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