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GASTROENTEROLOGY 2

Pharmacologic CategoryGeneric Brand ClassificationCommon IndicationsEssential Knowledge
Histamine (H2) antagonist famotidine (PO, IV) Pepcid, Zantac 360 PO: OTC GERD, erosive esophagitis, SUP Key Side Effects: headache, constipation, diarrhea, mental status changes
Dopamine (D2) antagonist metoclopramide (PO, IV) Reglan Gastroparesis, GERD, nausea, vomiting Key Side Effects: drowsiness, dystonia, akathisia, EPS, QTc prolongation, diarrhea, hyperprolactinemia
Selective serotonin (5-HT3) antagonist ondansetron (PO, IV) Zofran Nausea, vomiting Key Side Effects: headache, fatigue, constipation, QTc prolongation
Histamine (H1) antagonist promethazine (PO, IM, IV, PR) Phenergan Motion sickness, nausea, vomiting Key Side Effects: drowsiness, dry mouth, blurred vision, QTc prolongation, EPS
Histamine (H1) antagonist meclizine (PO) Bonine OTC Motion sickness, vertigo Key Side Effects: drowsiness, dry mouth, blurry vision
Antidiarrheal diphenoxylate and atropine (PO) Lomotil Diarrhea Key Side Effects: nausea, confusion, drowsiness, dizziness, xerostomia, tachycardia, urinary retention
Proton pump inhibitor (PPI) dexlansoprazole (PO) Dexilant GERD, PUD, erosive esophagitis, SUP Key Side Effects: headaches, abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia, increased risk of Clostridioides difficile associated diarrhea (CDAD)
Proton pump inhibitor (PPI) esomeprazole (PO, IV) Nexium PO: OTC GERD, PUD, erosive esophagitis, SUP Key Side Effects: headaches, abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia, increased risk of Clostridioides difficile associated diarrhea (CDAD)
Proton pump inhibitor (PPI) lansoprazole (PO) Prevacid OTC GERD, PUD, erosive esophagitis, SUP Key Side Effects: headaches, abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia, increased risk of Clostridioides difficile associated diarrhea (CDAD)
Proton pump inhibitor (PPI) omeprazole (PO) Prilosec OTC GERD, PUD, erosive esophagitis, SUP Key Side Effects: headaches, abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia, increased risk of Clostridioides difficile associated diarrhea (CDAD)
Proton pump inhibitor (PPI) pantoprazole (PO, IV) Protonix GERD, PUD, erosive esophagitis, SUP Key Side Effects: headaches, abdominal pain, nausea, diarrhea, bone fracture, vitamin B12 deficiency, hypomagnesemia, increased risk of Clostridioides difficile associated diarrhea (CDAD)
Gastrointestinal protectant sucralfate (PO) Carafate duodenal ulcers Key Side Effects: constipation, bezoar formation
Created by: arizvi
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