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GASTROENTEROLOGY 1

Pharmacologic CategoryGeneric Brand ClassificationCommon IndicationsEssential Knowledge
Anticholinergic; Antispasmodic dicyclomine (PO) Bentyl IBS Key Side Effects: drowsiness, blurred vision, dizziness, xerostomia, constipation
Guanylate cyclase C agonist linaclotide (PO) Linzess IBS-C, opioid-induced constipation Key Side Effects: diarrhea, abdominal pain
Osmotic laxative polyethylene glycol 3350 (PO) MiraLax OTC Constipation Key Side Effects: abdominal cramping, electrolyte imbalance
Osmotic laxative Lactulose (PO) Enulose, Constulose Constipation, hepatic encephalopathy Key Side Effects: abdominal cramps, abdominal distention, diarrhea, flatulence
Stimulant laxative senna (PO) Ex-Lax, Senokot OTC Constipation Key Side Effects: abdominal cramping, electrolyte imbalance
Stool softener docusate (PO) Colace OTC Prevent straining during defecation Other Notes: do not use with mineral oil
Corticosteroid dexamethasone (PO, IV) DexPak, DoubleDex Inflammatory diseases, cerebral edema, CINV Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use)
Corticosteroid methylprednisolone (PO, IM, IV) Medrol, Solu-Medrol Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use)
Corticosteroid prednisolone (PO) Orapred Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use)
Corticosteroid prednisone (PO) Deltasone, Rayos Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use)
Corticosteroid hydrocortisone (PO, IV, topical) Topical: Cortaid IV: Solu-Cortef Topical: OTC Topical: Inflammation, rash PO/IV: Acute illness, adrenal insufficiency Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use)
Created by: arizvi
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