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CNS 3
CENTRAL NERVOUS SYSTEM 3
| Pharmacologic Category | Generic | Brand | Classification | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| Antimanic agent | lithium (PO) | Lithobid | Bipolar disorder | Key Side Effects: tremor, acne, hypothyroidism, weight gain, polyuria, polydipsia, GI upset | |
| Antimigraine | sumatriptan (PO, intranasal, SQ) | Imitrex | Migraine | Key Side Effects: fatigue, somnolence, dizziness, chest tightness, paresthesias | |
| Antimigraine | rizatriptan (PO) | Maxalt | Migraine | Key Side Effects: fatigue, somnolence, dizziness, chest tightness, paresthesias | |
| First-generation antipsychotic | haloperidol (PO, IV, IM) | Haldol | Schizophrenia | Key Side Effects: sedation, EPS, parkinsonism, xerostomia, orthostatic hypotension, weight gain, QTc prolongation | |
| Second-generation antipsychotic | clozapine (PO) | Clozaril | Treatment-resistant schizophrenia | Key Side Effects: sedation, constipation, orthostatic hypotension, sialorrhea, hyperglycemia, weight gain, neutropenia | |
| Second-generation antipsychotic | aripiprazole (PO, IM) | PO/IM: Abilify; IM: Aristada | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Key Side Effects: akathisia, restlessness, sedation, EPS, constipation, orthostatic hypotension, weight gain | |
| Second-generation antipsychotic | quetiapine (PO) | Seroquel, Seroquel XR | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Key Side Effects: sedation, EPS, constipation, orthostatic hypotension, weight gain | |
| Second-generation antipsychotic | lurasidone (PO) | Latuda | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Key Side Effects: sedation, EPS, constipation, orthostatic hypotension, weight gain | |
| Second-generation antipsychotic | olanzapine (PO, IM) | Zyprexa | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Key Side Effects: sedation, EPS, constipation, orthostatic hypotension, weight gain | |
| Second-generation antipsychotic | risperidone (PO, IM) | PO: Risperdal IM: Risperdal Consta | Schizophrenia | Key Side Effects: sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia |