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ENDOCRINE 3
| Pharmacologic Category | Generic | Brand | Classification | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| Androgen | testosterone gel (topical) | AndroGel, Fortesta, Vogelxo | CS-III | Male hypogonadism | Key Side Effects: contact dermatitis, acne, increased prostate specific antigen (PSA), emotional lability, hypertension |
| Bisphosphonate | alendronate (PO) | Fosamax | Osteoporosis | Key Side Effects: dyspepsia, gastroesophageal reflux disease, hypocalcemia, atypical fractures, osteonecrosis of the jaw | |
| Vitamin D analog | cholecalciferol (vitamin D3) (PO) | OTC | Dietary supplement, osteoporosis prevention | Key Side Effect: vitamin D toxicity (nausea, vomiting, loss of appetite, constipation, confusion, weakness) Other Note: CI with hypercalcemia | |
| Phosphodiesterase-5 enzyme (PDE5) inhibitor | sildenafil (PO) | Viagra, Revatio | ED, PAH | Key Side Effects: priapism, headache, flushing, visual disturbance, dyspepsia, back pain (mostly with tadalafil), hearing or vision loss (rare) Other Notes: CI with concomitant use of nitrates (may cause severe hypotension) | |
| Phosphodiesterase-5 enzyme (PDE5) inhibitor | tadalafil (PO) | Cialis, Adcirca | ED, BPH, PAH | Key Side Effects: priapism, headache, flushing, visual disturbance, dyspepsia, back pain (mostly with tadalafil), hearing or vision loss (rare) Other Notes: CI with concomitant use of nitrates (may cause severe hypotension) | |
| Thyroid product | levothyroxine (PO, IV) | Synthroid, Levoxyl, Unithroid | Hypothyroidism | Key Side Effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance US Boxed Warnings: not intended for use for weight loss | |
| Thyroid product | thyroid, desiccated (PO) | Armour Thyroid | Hypothyroidism | Key Side Effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance US Boxed Warnings: not intended for use for weight loss | |
| CNS stimulant, anorexiant | phentermine (PO) | Adipex-P | Obesity | Key Side Effects: tachycardia, hypertension, nausea, dizziness, xerostomia, agitation |