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ENDOCRINE 2
| Pharmacologic Category | Generic | Brand | Classification | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| Contraceptive | drospirenone and ethinyl estradiol (PO) | Yasmin 28, Yaz | Contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke | |
| Contraceptive | levonorgestrel and ethinyl estradiol (PO) | Lutera, Levora, Seasonique | Contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke | |
| Contraceptive | norethindrone and ethinyl estradiol (PO) | Junel, Loestrin, Microgestin | Contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke | |
| Contraceptive | norethindrone, ethinyl estradiol, and ferrous fumarate (PO) | Lo Loestrin Fe, Microgestin Fe | Contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke | |
| Contraceptive | norgestimate and ethinyl estradiol (PO) | Tri-Sprintec, Sprintec | Contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke | |
| Contraceptive | norgestrel and ethinyl estradiol (PO) | Crysell-28, Low-Ogestrel Crysell-28, Low-Ogestrel | Contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke | |
| Estrogen derivative | estrogens, conjugated (equine) (PO, topical) | Premarin | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | Key Side Effects: irritation at application site (transdermal patch only), edema, abdominal pain, breast tenderness, weight gain, thromboembolic disorders (myocardial infarction, stroke, VTE) | |
| Estrogen derivative | estradiol (transdermal, PO) | Transdermal: Climera, Vivelle Dot PO: Estrace | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | Key Side Effects: irritation at application site (transdermal patch only), edema, abdominal pain, breast tenderness, weight gain, thromboembolic disorders (myocardial infarction, stroke, VTE) | |
| Progestin | medroxyprogesterone (PO) | Provera | Abnormal uterine bleeding, secondary amenorrhea | Key Side Effects: acne, abnormal menstrual bleeding, headache, amenorrhea, weight gain |