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CARDIOVASCULAR 4

Pharmacologic CategoryGeneric NameBrand NameClassificationCommon IndicationsEssential Knowledge
Antiarrhythmic amiodarone (PO, IV) Pacerone, Nexterone AF (rhythm control), ventricular fibrillation, ventricular tachycardia Key Side Effects: hypothyroidism, hyperthyroidism, pulmonary toxicity, hepatotoxicity, epithelial keratopathy, photosensitivity US Boxed Warnings: intended only for life-threatening arrhythmias; pulmonary toxicity, hepatotoxicity; proarrhythmic
Cholesterol absorption inhibitor ezetimibe (PO) Zetia Dyslipedemia Key Side Effects: myalgias, diarrhea
Fibric acid derivative fenofibrate (PO) Tricor, Trilipix Hypertriglyceridemia Key Side Effects: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases
Fibric acid derivative gemfibrozil (PO) Lopid Hypertriglyceridemia Key Side Effects: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases
HMG-CoA reductase inhibitor atorvastatin Lipitor Dyslipidemia, CAD, stroke Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding
HMG-CoA reductase inhibitor lovastatin Altoprev Dyslipidemia, CAD, stroke Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding
HMG-CoA reductase inhibitor pravastatin Pravachol Dyslipidemia, CAD, stroke Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding
HMG-CoA reductase inhibitor rosuvastatin Crestor Dyslipidemia, CAD, stroke Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding
HMG-CoA reductase inhibitor simvastatin Zocor Dyslipidemia, CAD, stroke Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding
Omega-3 fatty acids omega-3 ethyl esters (PO) Lovaza OTC: available Rx: Lovaza & Vascepa Hypertriglyceridemia Key Side Effects: dyspepsia, eructation, fishy aftertaste Other Notes: can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy
Omega-3 fatty acids icosapent ethyl (PO) Vascepa OTC: available Rx: Lovaza & Vascepa Hypertriglyceridemia Key Side Effects: eructation, arthralgia Other Notes: can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy
Created by: arizvi
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