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CARDIOVASCULAR 1
| Pharmacologic Category | Generic | Brand | Classification | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| Angiotensin-converting enzyme (ACE) inhibitor | benazepril (PO) | Lotensin | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) | |
| Angiotensin-converting enzyme (ACE) inhibitor | enalapril (PO) | Vasotec | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) | |
| Angiotensin-converting enzyme (ACE) inhibitor | lisinopril (PO) | Prinivil, Zestril | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) | |
| Angiotensin-converting enzyme (ACE) inhibitor | ramipril | Altace | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) | |
| Angiotensin II receptor blocker (ARB) | irbesartan | Avapro | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) | |
| Angiotensin II receptor blocker (ARB) | losartan | Cozaar | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) | |
| Angiotensin II receptor blocker (ARB) | olmesartan | Benicar | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) | |
| Angiotensin II receptor blocker (ARB) | valsartan | Diovan | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) | |
| ARB and neprilysin inhibitor (ARNI) | valsartan and sacubitril (PO) | Entresto | HF | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) Other Notes: Do not use within 36 hours of an ACE inhibitor | |
| Dihydropyridine calcium channel blocker (CCB) | amlodipine (PO) | Norvasc | HTN, CAD | Key Side Effects: peripheral edema, hypotension | |
| Dihydropyridine calcium channel blocker (CCB) | nifedipine ER (PO) | Procardia XL, Adalat CC | HTN, CAD | Key Side Effects: peripheral edema, hypotension | |
| Dihydropyridine calcium channel blocker (CCB) | nicardipine (PO, IV) | Cardene | Hypertensive crisis | Key Side Effects: flushing, headache, peripheral edema, hypotension | |
| Non-dihydropyridine CCB | diltiazem (PO, IV) | Cartia XT, Cardizem CD, Cardizem LA, Cardizem, Tiazac | AF (rate control), HTN, CAD | Key Side Effects: bradycardia, constipation, peripheral edema, hypotension | |
| Non-dihydropyridine CCB | verapamil (PO) | Calan SR, Verelan | AF (rate control), HTN, CAD | Key Side Effects: bradycardia, constipation, peripheral edema, hypotension | |
| Thiazide diuretic | hydrochlorothiazide (PO) | HTN | Key Side Effects: hypokalemia, hyponatremia, photosensitivity, hypotension | ||
| Thiazide-related diuretic | chlorthalidone (PO) | Thalitone | HTN | Key Side Effects: hypokalemia, hyponatremia, photosensitivity, hypotension | |
| Dihydropyridine calcium channel blocker (CCB) and Angiotensin-converting enzyme (ACE) inhibitor | amlodipine and benazepril (PO) | Lotrel | HTN, HF, CAD | ||
| Angiotensin-converting enzyme (ACE) inhibitor and Thiazide diuretic | lisinopril and hydrochlorothiazide (PO) | Zestoretic | HTN, HF, CAD | ||
| Angiotensin II receptor blocker (ARB) and Thiazide diuretic | losartan and hydrochlorothiazide (PO) | Hyzaar | HTN, HF, CAD | ||
| Angiotensin II receptor blocker (ARB) and Thiazide diuretic | olmesartan and hydrochlorothiazide (PO) | Benicar-HCT | HTN, HF, CAD | ||
| Angiotensin II receptor blocker (ARB) and Thiazide diuretic | valsartan and hydrochlorothiazide (PO) | Diovan-HCT | HTN, HF, CAD |