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DEENT 2
| Pharmacologic Category | Generic | Brand | Classification | Common Indication | Essential Knowledge |
|---|---|---|---|---|---|
| Alpha (α1) agonist | pseudoephedrine (PO) | Sudafed | OTC | Nasal congestion | Key Side Effects: Increased blood pressure, tachycardia, palpitations, insomnia, restlessness Other notes: sold behind the counter, avoid during first trimester of pregnancy |
| Corticosteroid | fluticasone (intranasal) | Flonase | OTC | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| Corticosteroid | triamcinolone (intranasal) | Nasacort | OTC | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| Histamine (H1) blocker | azelastine (intranasal) | Astepro | OTC | Allergic rhinitis | Key Side Effects: headache, nasal dryness, epistaxis, bitter taste, drowsiness |
| Histamine (H1) blocker | diphenhydramine (PO, IV) | Benadryl | PO: OTC | Allergic rhinitis, allergic reaction, insomnia | Key Side Effects: drowsiness, constipation, xerostomia, urinary retention, cognitive impairment Other Notes: for OTC use, do NOT use in children < 6 years of age |
| Histamine (H1) blocker | hydroxyzine (PO, IV) | Atarax, Vistaril | Pruritus, nausea, anxiety | Key Side Effects: dizziness, somnolence, xerostomia, blurred vision, QTc prolongation | |
| Histamine (H1) blocker | cetirizine | Zyrtec | OTC | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | loratadine | Claritin | OTC | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | fexofenadine | Allegra | OTC | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| Histamine (H1) blocker | levocetirizine (PO) | Xyzal | OTC | Allergic rhinitis | Key Side Effects: diarrhea, drowsiness, headache |
| Histamine (H1) blocker | olopatadine (ophthalmic) | Pataday, Patanol | OTC | Allergic conjunctivitis | Key Side Effects: ocular burning, discomfort, dryness |
| Histamine (H1) blocker and opioid analgesic | promethazine and codeine (PO) | Phenergan with Codeine | CS-V | Cough | Key Side Effects: dizziness, somnolence, xerostomia, blurred vision, constipation, respiratory depression (dose-related) |
| Opioid analgesic and expectorant | codeine and guaifenesin (PO) | Robitussin AC, Cheratussin AC | CS-V | Cough | Key Side Effects: dizziness, somnolence, constipation, respiratory depression (dose-related) |