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CNS 3

Central Nervous System 3

Pharmacologic CategoryGeneric NameBrand NameCommon Indicators
Antimanic agent lithium (PO) Lithobid Bipolar disorder Key Side Effects: tremor, acne, hypothyroidism, weight gain, polyuria, polydipsia, GI upset US Boxed Warnings: ability to promptly monitor levels is necessary Other Notes: narrow therapeutic index drug; avoid in pregnancy
Antimigraine sumatriptan (PO, intranasal, SQ) Imitrex Migraine Key Side Effects: fatigue, somnolence, dizziness, chest tightness, paresthesias Other Notes: CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension
Antimigraine rizatriptan (PO) Maxalt Migraine Key Side Effects: fatigue, somnolence, dizziness, chest tightness, paresthesias Other Notes: CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension
First-generation antipsychotic haloperidol (PO, IV, IM) Haldol Schizophrenia Key Side Effects: sedation, EPS, parkinsonism, xerostomia, orthostatic hypotension, weight gain, QTc prolongation US Boxed Warnings: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Second-generation antipsychotic clozapine (PO) Clozaril Treatment-resistant schizophrenia Key Side Effects: sedation, constipation, orthostatic hypotension, sialorrhea, hyperglycemia, weight gain, neutropenia US Boxed Warnings: may cause severe neutropenia; may cause orthostatic hypotension, bradycardia, and syncope; may cause seizures
Second-generation antipsychotic aripiprazole (PO, IM) PO/IM: Abilify; IM: Aristada Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) Key Side Effects: akathisia, restlessness, sedation, EPS, constipation, orthostatic hypotension, weight gain US Boxed Warnings: antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults
Second-generation antipsychotic quetiapine (PO) Seroquel, Seroquel XR Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) Key Side Effects: sedation, EPS, constipation, orthostatic hypotension, weight gain US Boxed Warnings: antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults
Second-generation antipsychotic lurasidone (PO) Latuda Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) Key Side Effects: sedation, EPS, constipation, orthostatic hypotension, weight gain US Boxed Warnings: antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults
Second-generation antipsychotic olanzapine (PO, IM) Zyprexa Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) Key Side Effects: sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia US Boxed Warnings: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Second-generation antipsychotic risperidone (PO, IM) PO: Risperdal IM: Risperdal Consta Schizophrenia Key Side Effects: sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia US Boxed Warnings: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Created by: kimchii
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