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CNS 1

Central Nervous System 1

Pharmacologic CategoryGeneric NameBrand NameCommon Indicators
Alpha₂ antagonist mirtazapine (PO) Remeron MDD Key Side Effects: drowsiness, weight gain, xerostomia, increased appetite, constipation US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Norepinephrine- dopamine reuptake inhibitor bupropion (PO) Wellbutrin SR, Wellbutrin XL MDD Key Side Effects: tachycardia, headache, agitation, dizziness, insomnia, weight loss, xerostomia US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults; serious neuropsychiatric reactions may occur
Selective norepinephrine reuptake inhibitor atomoxetine (PO) Strattera ADHD Key Side Effects: hypertension, tachycardia, headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia US Boxed Warnings: increased risk of suicidal ideation in children or adolescents Other Notes: CI within 14 days of MAOI
Serotonin- norepinephrine reuptake inhibitor (SNRI) desvenlafaxine (PO) Pristiq MDD Key Side Effects: headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warnings: increased risk of suicidal behavior in children, adolescents, and young adults
Serotonin- norepinephrine reuptake inhibitor (SNRI) duloxetine (PO) Cymbalta MDD, neuropathic pain Key Side Effects: headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warnings: increased risk of suicidal behavior in children, adolescents, and young adults
Serotonin- norepinephrine reuptake inhibitor (SNRI) venlafaxine (PO) Effexor XR MDD Key Side Effects: headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warnings: increased risk of suicidal behavior in children, adolescents, and young adults
Selective serotonin reuptake inhibitor (SSRI) citalopram (PO) Celexa MDD Key Side Effects: drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Selective serotonin reuptake inhibitor (SSRI) fluoxetine (PO) Prozac MDD Key Side Effects: drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Selective serotonin reuptake inhibitor (SSRI) escitalopram (PO) Lexapro MDD Key Side Effects: drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Selective serotonin reuptake inhibitor (SSRI) paroxetine (PO) Paxil MDD Key Side Effects: drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Selective serotonin reuptake inhibitor (SSRI) sertraline (PO) Zoloft MDD Key Side Effects: drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Serotonin reuptake inhibitor trazodone (PO) Desyrel Insomnia, MDD Key Side Effects: sedation, headache, dizziness, xerostomia, nausea, priapism US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents and young adults
Tricyclic antidepressant (TCA) amitriptyline (PO) Elavil MDD, diabetic neuropathy, migraine prophylaxis Key Side Effects: dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, xerostomia, blurred vision, constipation US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Tricyclic antidepressant (TCA) nortriptyline (PO) Pamelor MDD, diabetic neuropathy, migraine prophylaxis Key Side Effects: dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, xerostomia, blurred vision, constipation US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults
Tricyclic antidepressant (TCA) doxepin (PO) Silenor Insomnia Key Side Effects: somnolence, sedation, nausea US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other Notes: CI within 14 days of MAOI; do not discontinue abruptly
Created by: kimchii
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