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PHO 2

Generic NameBrand NameClassificationPharmacologic CategoryCommon IndicationsEssential Knowledge
hydrocodone and acetaminophen (PO) Lortab, Vicodin, Norco CS-II Opioid and nonopioid analgesic combination Pain Key Side Effects: dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) US Boxed Warnings: use with CYP3A4 inhibitors (or stopping CYP3A4 inducers) can increase oxycodone concentrations; hepatotoxicity
oxycodone and acetaminophen (PO) Percocet, Endocet CS-II Opioid and nonopioid analgesic combination Pain Key Side Effects: dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) US Boxed Warnings: use with CYP3A4 inhibitors (or stopping CYP3A4 inducers) can increase oxycodone concentrations; hepatotoxicity
codeine and acetaminophen (PO) Tylenol with Codeine #3, Tylenol with Codeine #4 CS-III Opioid and nonopioid analgesic combination Pain ide Effects: dizziness, drowsiness, nausea, constipation, itching, respiratory depression Boxed Warnings: caution with CYP3A4/2D6 drugs; fatal respiratory depression in some children; liver toxicity
naloxone (IV, IM, SQ, intranasal) Narcan Nasal Spray, Zimhi Narcan Nasal Spray: OTC Opioid antagonist Opioid overdose Key Side Effects: opioid withdrawal syndrome in opioid-dependent populations, pain
buprenorphine and naloxone (SL) Suboxone CS-III Partial opioid agonist and opioid antagonist Opioid use disorder Side Effects: withdrawal in opioid-dependent patients, constipation, headache, sweating Notes: risk of serious respiratory depression with other CNS depressants; naloxone helps prevent misuse by triggering withdrawal if injected
ferrous sulfate (PO) FeroSul, SlowFe OTC Iron supplement Iron deficiency anemia Key Side Effects: nausea, stomach upset, constipation (dose-related), dark and tarry stools US Boxed Warning: accidental overdose of iron is leading cause of fatal poisoning in children under 6 years old
cyanocobalamin (vitamin B12) (PO, IM, SL, intranasal) n/a PO, SL: OTC Water-soluble vitamin Vitamin B12 deficiency (manifests as macrocytic anemia) Key Side Effects: no major side effects
folic acid (PO) n/a OTC Water-soluble vitamin Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy Key Side Effects: no major side effects
Created by: user-1745497
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