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CNS 4
| Generic Name | Brand Name | Classification | Pharmacologic Category | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| carbamazepine (PO) | Tegretol | Anticonvulsant | Seizure disorders, bipolar disorder | Side Effects: dizziness, drowsiness, headache, ataxia, N/V, low sodium Boxed Warnings: risk of SJS/TEN; rare blood disorders (aplasia, agranulocytosis) | |
| lamotrigine (PO) | Lamictal | Anticonvulsant | Seizure disorders, bipolar disorder | Key Side Effects: nausea, vomiting, somnolence, skin rash, alopecia US Boxed Warnings: risk of serious dermatologic reactions, including SJS | |
| divalproex (valproic acid derivative) (PO) | Depakote, Depakote ER | Anticonvulsant | Seizure disorders, bipolar disorder, migraine prophylaxis | Key Side Effects: drowsiness, weight gain, tremor, alopecia, thrombocytopenia, hyperammonemia US Boxed Warnings: may cause fatal hepatic failure; may cause life-threatening pancreatitis; fetal toxicity | |
| topiramate (PO) | Topamax | Anticonvulsant | Seizure disorders, migraine prophylaxis | Key Side Effects: somnolence, dizziness, memory impairment, weight loss | |
| levetiracetam (PO, IV) | Keppra | Anticonvulsant | Seizure disorders | Key Side Effects: somnolence, dizziness, nausea, vomiting, weakness, asthenia, psychotic symptoms, agitation | |
| oxcarbazepine (PO) | Trileptal | Anticonvulsant | Seizure disorders | Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, hyponatremia | |
| gabapentin (PO) | Neurontin | Anticonvulsant | Seizure disorders, neuropathic pain | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain | |
| pregabalin (PO) | Lyrica | CS-V | Anticonvulsant | Seizure disorders, neuropathic pain | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain |