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CNS 2
| Generic Name | Brand Name | Classification | Pharmacologic Category | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| dexmethylphenidate (PO) | Focalin, Focalin XR | CS-II | CNS stimulant | ADHD | Key Side Effects: insomnia, headache, anxiety, weight loss, decreased appetite, hypertension US Boxed Warnings: high potential for abuse Other Notes: CI within 14 days of MAOI |
| dextroamphetamine and amphetamine (PO) | Adderall, Adderall XR | CS-II | CNS stimulant | ADHD, narcolepsy | Key Side Effects: insomnia, headache, anxiety, weight loss, decreased appetite, hypertension US Boxed Warnings: high potential for abuse Other Notes: CI within 14 days of MAOI |
| lisdexamfetamine (PO) | Vyvanse | CS-II | CNS stimulant | ADHD | Key Side Effects: insomnia, headache, anxiety, weight loss, decreased appetite, hypertension US Boxed Warnings: high potential for abuse Other Notes: CI within 14 days of MAOI |
| methylphenidate (PO, transdermal) | PO: Concerta, Ritalin Patch: Daytrana | CS-II | CNS stimulant | ADHD, narcolepsy | Key Side Effects: insomnia, headache, anxiety, weight loss, decreased appetite, hypertension US Boxed Warnings: high potential for abuse Other Notes: CI within 14 days of MAOI |
| guanfacine (PO) | Intuniv | Selective alpha2a agonist | ADHD, HTN | Key Side Effects: bradycardia, hypotension, sedation, skin rash, xerostomia, constipation Other Notes: do not abruptly discontinue | |
| pramipexole (PO) | Mirapex | Dopamine agonist | Parkinson's disease, RLS | Key Side Effects: nausea, hallucinations, dizziness, drowsiness, compulsive behaviors, orthostasis | |
| ropinirole (PO) | Requip | Dopamine agonist | Parkinson's disease, RLS | Key Side Effects: nausea, hallucinations, dizziness, drowsiness, compulsive behaviors, orthostasis | |
| carbidopa and levodopa (PO) | Sinemet, Sinemet CR | Decarboxylase inhibitor (carbidopa), dopamine precursor (levodopa) | Parkinson's disease | Key Side Effects: nausea, orthostatic hypotension, dyskinesias Other Notes: CI within 14 days of MAOI, CI in narrow-angle glaucoma; do not abruptly discontinue | |
| memantine (PO) | Namenda | N-methyl D-aspartate (NMDA) antagonist | Dementia | Key Side Effects: constipation, confusion, dizziness, headache | |
| donepezil (PO, transdermal) | PO: Aricept, Transdermal: Adlarity | Cholinesterase inhibitor | Dementia | Key Side Effects: nausea, vomiting, diarrhea |