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Endocrine 3
| Generic Name | Brand Name | Classification | Pharmacologic Category | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| testosterone gel (topical) | AndroGel, Fortesta, Vogelxo | CS-III | Androgen | Male hypogonadism | Side Effects: skin irritation, acne, ↑ PSA, mood changes, HTN Boxed Warning: secondary exposure → virilization (esp. kids) Notes: CI in prostate/breast cancer, pregnancy; apply in AM |
| alendronate (PO) | Fosamax | Bisphosphonate | Osteoporosis | Side Effects: indigestion, reflux, low calcium, atypical fractures, jaw necrosis Notes: CI in hypocalcemia/esophageal issues; take ≥30 min before food with water; stay upright 30 min | |
| cholecalciferol (vitamin D3) (PO) | n/a | OTC | Vitamin D analog | Dietary supplement, osteoporosis prevention | Key Side Effect: vitamin D toxicity (nausea, vomiting, loss of appetite, constipation, confusion, weakness) Other Note: CI with hypercalcemia |
| sildenafil (PO) | Viagra, Revatio | Phosphodiesterase-5 enzyme (PDE5) inhibitor | ED, PAH | Key Side Effects: priapism, headache, flushing, visual disturbance, dyspepsia, back pain (mostly with tadalafil), hearing or vision loss (rare) Other Notes: CI with concomitant use of nitrates (may cause severe hypotension) | |
| tadalafil (PO) | Cialis, Adcirca | Phosphodiesterase-5 enzyme (PDE5) inhibitor | ED, BPH, PAH | Key Side Effects: priapism, headache, flushing, visual disturbance, dyspepsia, back pain (mostly with tadalafil), hearing or vision loss (rare) Other Notes: CI with concomitant use of nitrates (may cause severe hypotension) | |
| levothyroxine (PO, IV) | Synthroid, Levoxyl, Unithroid | Thyroid product | Hypothyroidism | Side Effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance Boxed Warning: not for weight loss Notes: narrow TI; monitor levels; generics may vary | |
| thyroid, desiccated (PO) | Armour Thyroid | Thyroid product | Hypothyroidism | Side Effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance Boxed Warning: not for weight loss Notes: narrow TI; monitor levels; generics may vary | |
| phentermine (PO) | Adipex-P | CNS stimulant, anorexiant | Obesity | Side Effects: fast HR, high BP, nausea, dizziness, dry mouth, agitation Notes: short-term use only; CI in CVD, drug abuse, pregnancy, hyperthyroidism, MAOI use (≤14 days) |