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Endocrine 2
| Generic Name | Brand Name | Pharmacologic Category | Common Indications | Essential Knowledge |
|---|---|---|---|---|
| drospirenone and ethinyl estradiol (PO) | Yasmin 28, Yaz | Contraceptive | Contraception, acne | Side Effects: nausea, breast tenderness, headache, weight gain, menstrual changes, clots Boxed Warning: ↑ CV risk in women >35 who smoke Notes: CI in liver disease, clots, breast cancer, migraines w/ aura, CVD |
| levonorgestrel and ethinyl estradiol (PO) | Lutera, Levora, Seasonique | Contraceptive | Contraception, acne | Side Effects: nausea, breast tenderness, headache, weight gain, menstrual changes, clots Boxed Warning: ↑ CV risk in women >35 who smoke Notes: CI in liver disease, clots, breast cancer, migraines w/ aura, CVD |
| norethindrone and ethinyl estradiol (PO) | Junel, Loestrin, Microgestin | Contraceptive | Contraception, acne | Side Effects: nausea, breast tenderness, headache, weight gain, menstrual changes, clots Boxed Warning: ↑ CV risk in women >35 who smoke Notes: CI in liver disease, clots, breast cancer, migraines w/ aura, CVD |
| norethindrone, ethinyl estradiol, and ferrous fumarate (PO) | Lo Loestrin Fe, Microgestin Fe | Contraceptive | Contraception, acne | Side Effects: nausea, breast tenderness, headache, weight gain, menstrual changes, clots Boxed Warning: ↑ CV risk in women >35 who smoke Notes: CI in liver disease, clots, breast cancer, migraines w/ aura, CVD |
| norgestimate and ethinyl estradiol (PO) | Tri-Sprintec, Sprintec | Contraceptive | Contraception, acne | Side Effects: nausea, breast tenderness, headache, weight gain, menstrual changes, clots Boxed Warning: ↑ CV risk in women >35 who smoke Notes: CI in liver disease, clots, breast cancer, migraines w/ aura, CVD |
| norgestrel and ethinyl estradiol (PO) | Crysell-28, Low-Ogestrel | Contraceptive | Contraception, acne | Side Effects: nausea, breast tenderness, headache, weight gain, menstrual changes, clots Boxed Warning: ↑ CV risk in women >35 who smoke Notes: CI in liver disease, clots, breast cancer, migraines w/ aura, CVD |
| estrogens, conjugated (equine) (PO, topical) | Premarin | Estrogen derivative | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | SE's: site irritation (patch), edema, abd pain, breast tenderness, weight gain, clots (MI, stroke, VTE) BBW: ↑ endometrial/ breast cancer risk, not for dementia or CVD prevention Notes: CI in liver disease, clots, CVD, breast cancer, estrogen-dep.tumors |
| estradiol (transdermal, PO) | Transdermal: Climera, Vivelle Dot PO: Estrace | Estrogen derivative | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | SE's: site irritation (patch), edema, abd pain, breast tenderness, weight gain, clots (MI, stroke, VTE) BBW: ↑ endometrial/ breast cancer risk, not for dementia or CVD prevention Notes: CI in liver disease, clots, CVD, breast cancer, estrogen-dep.tumors |
| medroxyprogesterone (PO) | Provera | Progestin | Abnormal uterine bleeding, secondary amenorrhea | Side Effects: acne, irregular bleeding, headache, amenorrhea, weight gain Boxed Warnings: ↑ breast cancer risk; not for dementia or CVD prevention Notes: CI in clots, CVD, hormone-dependent tumors, abnormal bleeding, liver issues |