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Pharm Exam 4

TermDefinition
MOA: Furosemide Loop Diuretic: Acts on ascending loop of Henle to block sodium and chloride reabsorbtion
Therapeutic Uses: Furosemide Pulmonary Edema associated with CHF, used when CHF edema not responsive to less powerful diuretics. **Can promote diuresis even with severe renal impairment
Adverse Effects: Furosemide Dehydration, hypokalemia, hypotension, ototoxicity
Medications in class: Loop Diuretics Furosemide, bumetanide, torsemide
MOA: Hyrdochlorothiazide Thiazide Diuretic: Acts on early segment of distal convoluted tubule; increases secretion of sodium and water
Therapeutic uses: Hydrochlorothiazide Essential HTN, Edema related to CHF
Adverse Effects: Hydrochlorothiazide Dehydration, hypokalemia, hypotension
MOA: Spironolactone Potassium Sparing Diuretic: Blocks the action of aldosterone in distal nephron, leading to potassium retention, sodium excretion
Therapeutic Uses: Sprionolactone HTN, Edema, CHF
Adverse Effects: Sprionolactone Hyperkalemia, endocrine effects
What class is Triamterene? How does it differ from the other mediation in this class? Potassium Sparing Diuretic; Significantly faster onset than spironolactone (2-4hr vs. 24-48hr).
Created by: brownkira40
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