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CV 4
| Generic Name | Brand Name | Classification | Pharmacologic Category | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| amiodarone (PO, IV) | Pacerone, Nexterone | Antiarrhythmic | AF (rhythm control), ventricular fibrillation, ventricular tachycardia | Side Effects: Hypo-/hyperthyroidism, pulm/hepatotoxicity, epithelial keratopathy, photosensitivity Boxed Warnings: For life-threatening arrhythmias only; risk of pulm/hepatotoxicity, proarrhythmia Notes: Many drug interactions | |
| ezetimibe (PO) | Zetia | Cholesterol absorption inhibitor | Dyslipidemia | Key Side Effects: myalgias, diarrhea | |
| fenofibrate (PO) | Tricor, Trilipix | Fibric acid derivative | Hypertriglyceridemia | Key Side Effects: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases | |
| gemfibrozil (PO) | Lopid | Fibric acid derivative | Hypertriglyceridemia | Key Side Effects: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases | |
| atorvastatin (PO) | Lipitor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| lovastatin (PO) | Altoprev | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| pravastatin (PO) | Pravachol | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| rosuvastatin (PO) | Crestor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| simvastatin (PO) | Zocor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| omega-3 ethyl esters (PO) | Lovaza | OTC: available Rx: Lovaza & Vascepa | Omega-3 fatty acids | Hypertriglyceridemia | Key Side Effects: dyspepsia, eructation, fishy aftertaste Other Notes: can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |
| icosapent ethyl (PO) | Vascepa | OTC: available Rx: Lovaza & Vascepa | Omega-3 fatty acids | Hypertriglyceridemia | Key Side Effects: eructation, arthralgia Other Notes: can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |