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DEENT 2
| Generic Name | Brand Name | Classification | Pharmacologic Category | Common Indications | Essential Knowledge |
|---|---|---|---|---|---|
| pseudoephedrine (PO) | Sudafed | OTC | Alpha (α1) agonist | Nasal congestion | Key Side Effects: Increased blood pressure, tachycardia, palpitations, insomnia, restlessness Other notes: sold behind the counter, avoid during first trimester of pregnancy |
| fluticasone (intranasal) | Flonase | OTC | Corticosteroid | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| triamcinolone (intranasal) | Nasacort | OTC | Corticosteroid | Allergic rhinitis | Key Side Effects: nasal dryness, epistaxis, nasal burning, headache |
| azelastine (intranasal) | Astepro | OTC | Histamine (H1) blocker | Allergic rhinitis | Key Side Effects: headache, nasal dryness, epistaxis, bitter taste, drowsiness |
| diphenhydramine (PO, IV) | Benadryl | PO: OTC | Histamine (H1) blocker | Allergic rhinitis, allergic reaction, insomnia | Key Side Effects: drowsiness, constipation, xerostomia, urinary retention, cognitive impairment Other Notes: for OTC use, do NOT use in children < 6 years of age |
| hydroxyzine (PO, IV) | Atarax, Vistaril | Histamine (H1) blocker | Pruritus, nausea, anxiety | Key Side Effects: dizziness, somnolence, xerostomia, blurred vision, QTc prolongation | |
| cetirizine (PO) | Zyrtec | OTC | Histamine (H1) blocker | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| loratadine (PO) | Claritin | OTC | Histamine (H1) blocker | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| fexofenadine (PO) | Allegra | OTC | Histamine (H1) blocker | Allergic rhinitis | Key Side Effects: drowsiness, dizziness, headache |
| levocetirizine (PO) | Xyzal | OTC | Histamine (H1) blocker | Allergic rhinitis | Key Side Effects: diarrhea, drowsiness, headache |
| olopatadine (ophthalmic) | Pataday, Patanol | OTC | Histamine (H1) blocker | Allergic conjunctivitis | Key Side Effects: ocular burning, discomfort, dryness |
| promethazine and codeine (PO) | Phenergan with Codeine | CS-V | Histamine (H1) blocker and opioid analgesic | Cough | Key Side Effects: Dizziness, drowsiness, dry mouth, blurred vision, constipation, dose-related respiratory depression BBW: Opioids + CNS depressants (incl. alcohol) → sedation, respiratory depression, coma, and death Note: Not for use in <18 years |
| codeine and guaifenesin (PO) | Robitussin AC, Cheratussin AC | CS-V | Opioid analgesic and expectorant | Cough | Key Side Effects: dizziness, somnolence, constipation, respiratory depression (dose-related) Other Notes: opioid-containing cough and cold products no longer indicated for use in patients <18 years of age |