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CNS 1

BDK

Pharmacologic CategoryGeneric NameBrand NameCommon IndicationKey Side EffectsUSBWOther Notes
Alpha2 antagonist mirtazapine Remeron MDD drowsiness, weight gain, xerostomia, increased appetite, constipation increased risk of suicidal thinking and behavior in children, adolescents, and young adults ---
Norepinephrine-dopamine reuptake inhibitor bupropion Wellbutrin SR, Wellbutrin XL MDD tachycardia, headache, agitation, dizziness, insomnia, weight loss, xerostomia increased risk of suicidal thinking and behavior in children, adolescents, and young children; serious neuropsychiatric reactions have occurred use may increase risk of seizures (CI in patients w/ seizure disorders and/or eating disorders)
Selective norepinephrine reuptake inhibitor atomoxetine Strattera ADHD hypertension, tachycardia, headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia increased risk of suicidal ideation in children or adolescents CI within 14 days of MAOI
Serotonin-Norepinephrine reuptake inhibitor (SNRI) desvenlafaxine Pristiq MDD headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Serotonin-Norepinephrine reuptake inhibitor (SNRI) duloxetine Cymbalta MDD, neuropathic pain headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Serotonin-Norepinephrine reuptake inhibitor (SNRI) venlafaxine Effexor XR MDD headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Selective Serotonin reuptake inhibitor (SSRI) citalopram Celexa MDD drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Selective Serotonin reuptake inhibitor (SSRI) fluoxetine Prozac MDD drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI
Selective Serotonin reuptake inhibitor (SSRI) escitalopram Lexapro MDD drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Selective Serotonin reuptake inhibitor (SSRI) Paroxetine Paxil MDD drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Selective Serotonin reuptake inhibitor (SSRI) Sertraline Zoloft MDD drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Serotonin reuptake inhibitor trazodone Desyrel Insomnia, MDD sedation, headache, dizziness, xerostomia, nausea, priapism increased risk of suicidal thinking and behavior in children, adolescents, and young adults ---
Tricyclic antidepressant (TCA) amitriptyline Elavil MDD, diabetic neuropathy, migraine prophylaxis dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, xerostomia, blurred vision, constipation increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Tricyclic antidepressant (TCA) nortriptyline Pamelor MDD, diabetic neuropathy, migraine prophylaxis dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, xerostomia, blurred vision, constipation increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Tricyclic antidepressant (TCA) doxepin Silenor Insomnia somnolence, sedation, nausea increased risk of suicidal thinking and behavior in children, adolescents, and young adults CI within 14 days of MAOI; do not discontinue abruptly
Created by: TORICBC
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