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Endocrine 2
BDK
| Pharmacologic Category | Generic Name | Brand Name | Common Indication | Key Side Effects | BBW | Other Notes |
|---|---|---|---|---|---|---|
| Contraceptive | drospirenone and ethinyl estradiol | Yasmin 28, Yaz | Contraception, acne | nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain | increased risk of cardiovascular events in women > 35 yo who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease |
| Contraceptive | levonorgestrel and ethinyl estradiol | Lutera, Levora, Sesonique | Contraception, acne | nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain | increased risk of cardiovascular events in women > 35 yo who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease |
| Contraceptive | norethindrone and ethinyl estradiol | Junel, Loestrin, Microgestin | Contraception, acne | nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain | increased risk of cardiovascular events in women > 35 yo who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease |
| Contraceptive | norethindrone, ethinyl estradiol, and ferrous fumarate | Lo Loestrin Fe, Microgestin Fe | Contraception, acne | nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain | increased risk of cardiovascular events in women > 35 yo who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease |
| Contraceptive | norgestimate and ethinyl estadiol | Tri-Sprintec, Sprintec | Contraception, acne | nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain | increased risk of cardiovascular events in women > 35 yo who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease |
| Contraceptive | norgestrel and ethinyl estradiol | Crysell-28, Low-Ogestrel | Contraception, acne | nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache, weight gain | increased risk of cardiovascular events in women > 35 yo who smoke | CI in hepatic dysfunction, thromboembolic disorders, breast cancer, migraines with aura, and cardiovascular disease |
| Estrogen derivative | estrogens, conjugated (equine) | Premarin | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | edema, abdominal pain, breast tenderness, weight gain, thromboembolic disorders (MI, stoke, VTE) | increased risk of breast cancer, should not be used for dementia prevention, increased risk of endometrial cancer if not used concomitantly w/ progestin in women with uterus, should not be used to prevent CVD | CI in hepatic dysfunction, thromboembolic disorders, CVD, breast cancer, and estrogen-dependent tumor |
| Estrogen derivative | estradiol | Transdermal: Climera, Vivelle Dot; PO: Estrace | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | transdermal patch: irritation at application site; edema, abdominal pain, breast tenderness, weight gain, thromboembolic disorders (MI, stoke, VTE) | increased risk of breast cancer, should not be used for dementia prevention, increased risk of endometrial cancer if not used concomitantly w/ progestin in women with uterus, should not be used to prevent CVD | CI in hepatic dysfunction, thromboembolic disorders, CVD, breast cancer, and estrogen-dependent tumor |
| Progestin | medroxyprogesterone | Provera | Abnormal uterine bleeding, secondary amenorrhea | acne, abnormal mentstrual bleeding, headache, amenorrhea, weight gain | increased risk of breast cancer, should not be used for dementia prevention, should not be used for prevention of CVD | CI in thromboembolic disorders, cardiovascular disease, estrogen or progesterone-dependent tumors, undiagnosed abnormal genital bleeding, hepatic impairment |