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Cardio 4
BDK
| Pharmacologic Category | Generic Name | Brand Name | Common Indication | Essential Knowledge |
|---|---|---|---|---|
| Antiarrhythmic | amiodarone | Pacerone, Nexterone | AF (rhythm control), ventricular fibrillation, ventricular tachycardia | KSE: hypothyroidism, hyperthyroidism, pulmonary toxicity, hepatotoxicity, epithelial keratopathy, photosensitivity USBW: intended only for life-threatening arrhythmias; pulmonary toxicity, hepatotoxicity, proarrhythmic ON: many DI |
| Cholesterol absorption inhibitor | ezetimibe | Zetia | Dyslipidemia | KSE: myalgias, diarrhea |
| Fibric acid derivative | fenofibrate | Tricor, Trilipix | Hypertriglyceridemia | KSE: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases |
| Fibric acid derivative | gemfibrozil | Lopid | Hypertriglyceridemia | KSE: dyspepsia, myopathy/rhabdomyolysis, elevated transaminases |
| HMG-CoA reductase inhibitor | atorvastatin | Lipitor | Dyslipidemia, CAD, stroke | KSE: myopathy/rhabdomyolysis ON: avoid excessive grapefruit juice intake; avoid in pregnancy and breastfeeding |
| HMG-CoA reductase inhibitor | lovastatin | Altoprev | Dyslipidemia, CAD, stroke | KSE: myopathy/rhabdomyolysis ON: avoid excessive grapefruit juice intake; avoid in pregnancy and breastfeeding |
| HMG-CoA reductase inhibitor | pravastatin | Pravachol | Dyslipidemia, CAD, stroke | KSE: myopathy/rhabdomyolysis ON: avoid excessive grapefruit juice intake; avoid in pregnancy and breastfeeding |
| HMG-CoA reductase inhibitor | rosuvastatin | Crestor | Dyslipidemia, CAD, stroke | KSE: myopathy/rhabdomyolysis ON: avoid excessive grapefruit juice intake; avoid in pregnancy and breastfeeding |
| HMG-CoA reductase inhibitor | simvastatin | Zocor | Dyslipidemia, CAD, stroke | KSE: myopathy/rhabdomyolysis ON: avoid excessive grapefruit juice intake; avoid in pregnancy and breastfeeding |
| Omega-3 fatty acids | omega-3 ethyl esters | Lovaza | Hypertriglyceridemia | KSE: dyspepsia, eructation, fishy aftertaste ON: can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |
| Omega-3 fatty acids | icosapent ethyl | Vascepa | Hypertriglyceridemia | KSE: eructation, arthralgia ON: can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |