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Cardio 3

BDK

Pharmacologic CategoryGeneric NameBrand NameCommon IndicationEssential Knowledge
Anticoagulant, direct thrombin inhibitor dabigatran Pradaxa AF (stroke prevention), VTE KSE: bleeding, dyspepsia USBW: premature discontinuation increases risk of thrombotic events; increases risk of epidural/spinal hematoma in pts undergoing spinal puncture ON: swallow whole; dispense/store in original packaging; discard 4 mon. after open
Anticoagulant, factor Xa inhibitor apixaban Eliquis AF (stroke prevention), VTE KSE: bleeding USBW: premature discontinuation increases risk of thrombotic events; increased risk of epidural or spinal hematoma in patient undergoing spinal puncture
Anticoagulant, factor Xa inhibitor rivaroxoban Xarelto AF (stroke prevention), VTE, PAD KSE: bleeding USBW: premature discontinuation increases risk of thrombotic events; increases risk of epidural or spinal hematoma in patient undergoing spinal puncture
Anticoagulant, vitamin K antagonist warfarin Coumadin, Jantoven AF (stroke prevention), VTE KSE: bleeding, skin necrosis USBW: bleeding risk ON: narrow therapeutic index drug (toxicity may occur @ concentrations close to therapeutic range; monitoring recommended w/ INR); dose dependent table colors; consistent Vit K intake recom; many DI
Anticoagulant, low molecular weight heparin enoxaparin Lovenox ACS, VTE KSE: bleeding, HIT USBW: increased risk of epidural or spinal hematoma in patients undergoing spinal puncture ON: do not expel air bubble from syringe prior to injection
Anticoagulant heparin --- ACS, VTE KSE: bleeding, hyperkalemia (chronic use), HIT
Antiplatelet agent clopidogrel Plavix CAD, stroke KSE: bleeding USBW: diminished effectiveness in poor metabolizers
Antiplatelet agent ticagrelor Brilinta ACS KSE: bleeding, dyspnea USBW: significant, sometimes fatal bleeding; do not exceed aspirin >100 mg daily due to reduced ticagrelor effectiveness
Antiplatelet agent aspirin (OTC) Bayer, Bufferin, Ecotrin ACS, stable angina, pain, stroke KSE: dyspepsia, heartburn, bleeding ON: CI in NSAID or salicylate allergy, children and teenagers w/ viral infection (due to reye's syndrome), can cause tinnitus in salicylate overdose
Fibrinolytic altepase Intracatheter: Cathflo, Activase; IV: Activase Intracatheter: catheter clearance, IV: STEMI, acute ischemic stroke, PE KSE: bleeding ON: CI in patients with severe uncontrolled HTN
Vasodilator nitroglycerin (SL) Nitrostat ACS, stable angina KSE: headache, flushing, syncope, dizziness ON: do not use w/ PDE-5 inhibitors; tachyphylaxis (tolerance/decreases effectiveness); can aggravate angina causes by hypertrophic cardiomyopathy
Created by: TORICBC
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