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Antibiotic Types
Antibiotic type, Bactericidal/Bacteriostatic, and examples
| Type | Bactericidal/Bacteriostatic | Examples | Notes |
|---|---|---|---|
| Penicillins (Beta-Lactam Antibiotics with Cephalosporins) | Bactericidal | amoxicillin (Amoxil, Augmentin) | Side effects: ---Dermatologic: Rash ---GI: Diarrhea, nausea/vomiting ---Neurologic: headache ---Unnecessary/sustained use - antibiotic resistance -Work by damaging the cell wall of the bacteria (Bactericidal) -Treat wide range of infections |
| Cephalosporins (Beta-Lactam Antibiotics with Penicillins) | Bactericidal | cephalexin (Keflex), cefdinir (Omnicef), cefuroxime (Ceftin oral susp) | -Work by damaging the cell wall of the bacteria (bactericidal) -Treat wide range of infections like ear and sinus infections, UTIs, GI infections |
| Fluoroquinolones "Quinolones" | Bactericidal | ciprofloxacin (Cipro or Ciloxan (ophthalmic solution)), levofloxacin (Levaquin) | Side effects: ---GI: Dysgeusia (taste changes), nausea ---Neurologic: Headache, insomnia ---CV: QT prolongation ---BLACK BOX: peripheral neuropathy, tendonitis -Tread a wide range of infections like UTIs and respiratory infections, or resistant infec |
| Nitroimidazoles | Bactericidal | Metronidazole -- Flagyl | -Work by inhibiting bacterial nucleic acid synthesis -Treat a wide range of anaerobic infections, like GI, skin, UTIs, bone, blood, CNS, hear, and lower respiratory Antiprotozoal activity on parasites like trichromonas and amoeba |
| Nitrofurans | Bactericidal | Nitrofurantoin -- Macrodantin or Macrobid or Furadantin | Several mechanisms: disrupting bacterial protein, cell walls, RNA, and DNA synthesis (Bactericidal) --Nitrofurantoin has large crystal structure good for UTIs --Not appropriate for Elderly patients |
| Tetracyclines | Bactericidal | Doxycycline -- Vibramycin or Doryx | ยง Treat a wide range of infections, like intestinal, respiratory tract, urinary tract, and eyes Side effects: - Don't take with Dairy products or antacids because it will cause chelation -Tetracyclines Can cause photosensitivity |
| Sulfonamides "Sulfa Drugs" | Bacteriostatic | Sulfamethoxazole/Trimethoprim -- Bactrim or Septra | Work by inhibiting bacteria's ability to make folic acid, which is needed for reproduction (bacteriostatic) Treat a wide range of infections including UTIs, bronchitis and prostate infections |
| Macrolides "Erythromycin Antibiotics" | Bacteriostatic | Azithromycin -- Zithromax | Side effects: ---GI: abdominal pain, nausea, diarrhea ---Neurologic: headache, somnolence ---Cardiovascular (CV): QT prolongation ---Liver toxicity/jaundice -Treat a wide range of infections including UTIs, ear, resp tract |
| Lincosamides (lincomycin antibiotics) | Bacteriostatic | Clindamycin -- Cleocin | Work by inhibiting bacterial protein synthesis needed for replication Treat a wide range of anaerobic infections including dental, respiratory, skin, bone, and soft tissue infections --NOT related to macrolides, despite "-mycin" |
| Pseudomonic acids | Bacteriostatic | Mupirocin -- Bactroban cream or ointment | -Mupirocin is a mixture of several pseudomonic acids, which inhibit bacterial RNA and protein synthesis (bateriostatic) -Treats a wide range of skin infections typically due to Staph or Strep (impetigo, open wounds, MRSA |