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Onco. Ex 1

Categories

QuestionAnswer
Fluorouracil, Capecitabine Antimetabolites, pyrimidine antagonists
Mercaptopurine, Thioguanine Antimetabolites, purine antagonists
Methotrexate, Pemetrexed Antimetabolites, antifolates
1. Cytarabine, Gemcitabine, Trifluridine-tipiracil 2. Fludarabine, Cladribine, Clofarabine Antimetabolites, DNA polymerase; DNA elongation inhibitors 1. Pyrimidine analogs 2. Purine analogs
Azacitidine, Decitabine Antimetabolites, DNA methyltransferase inhibitors
Pentostatin, Hydroxyurea Antimetabolites, miscellaneous antimetabolites
Myelosuppression, GI toxicity (stomatitis, esophagitis, ulceration, diarrhea), Palmer-plantar erythrodysesthesia 5-FU, Capecitabine
5-FU, Capecitabine is [] eliminated renally
Capecitabine inhibits CYP2C9
Myelosuppression (dose limiting) Purine antagonists, Mercaptopurine and Thioguanine
Tumor lysis syndrome (Hematologic cancers, hyperuricemia) Mercaptopurine, Thioguanine
Myelosuppression, diarrhea, mucositis; ulcerative stomatitis, skin reactions Methotrexate
Myelosuppression (major) DNA Polymerase, DNA chain elongation inhibitors
Myelosuppression DNMT inhibitors
Created by: vlambert1797
Popular Pharmacology sets

 

 



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