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Pharmacology 1
Chapter 1,2,4,5
Question | Answer |
---|---|
Pharmacologia sen Manducto | First recorded reference to pharmacology written by Samuel Dale in 1693 |
Modern Pharmacology | Began in early 1800's, chemists isolated pharmacological subsstances from natural substances, effecs on animals studied, and early researchers used themselves as test subjects |
The Distinct Discipline | First department of pharmacoloogy est. at Estonia in 1847 |
John Jacob Abel | Father of American pharmacology, founder of pharmacology dept. at U of M in 1890 |
20th Century to Present | Drugs synthesized in laboratory, tested for relatively short time, understandin increased of how they produce their effects, and focus is on improvements in quality of life |
Pharmacology | greek for study of medicine, encompasses how drugs are aministered, where drugs travel in the body, and responses drugs produce |
Interrelated Subject Areas | ANP, Chem, Micro, and pathophysiology |
Characteristics of 10,000 drugs | Therapeutic applications, interactions, side effects, mechanisms of action |
Drugs elicit different responses depending on | age, sex, body mass, health status, genetics |
Therapeutics | concerned with the prevention of disease and treatment of suffering |
pharmacotherapy | the application of drugs for disease prevention and treatment of suffering |
chemical drugs | synthesized in a laboratory |
medication | a drug that is administered produce biological responses |
therapeutic response | a desirable response in the body |
adverse response | an undesirable response in the body |
biologics | agents naturally produced in animal cells, by microorganisms, or by the body itself |
examples of biologics | hormones, monoclonal antibodies, natural blood products and components, interferon, and vaccines |
Complementary and Alternative Therapies | Natural plant extracts, herbs, vitamins, minerals, dietary supplements, acupuncture, biofeedback |
OTC advantages | economical, no health-care appt. |
OTC disadvantages | may choose wrong drug, client my not know reactions or interactions, and innefective treatment may result in progression of disease |
prescription drugs | require that the recipient obtain a written order from a person with the legal authority to write such a prescription |
prescription drug advantages | health care provider examines the client and orders proper drug, amt and freq is controlled, instructions and on use side effects of drug are discussed |
prescription drug disadvantages | requires a prescription to obtain, need for health care provider |
formulary | the first standard list of drugs and drug recipes commonly used by pharmacists |
pharmacopoeia | a medical reference summarizing standards of a medical reference summarizing standars of drug purity, strength, and directions for synthesis |
United States Pharmacopoeia(USP) | first comprehensive publication of drug standards of purity, strength, directions for synthesis US 1820 |
American Pharmaceutical Organization (APhA) | National professional society of pharmacists 1852, maintained the national compendia of drug standards, the National Formulary (NF) |
National Formulary (NF) | national compendia of drug standard, competed with other compendia (USP) |
USP-NF | merged in 1975, offical monographs and interim announcements published regularly, full bound version printed every five years |
Biologic Control Act of 1902 | standardized serum and blood-related products |
Pure food and Drug Act of 1906 | government controls labeling of medicines |
Sherley Amendment of 1912 | prohibited drugs labeled with false therapeutic claims |
Food, Drug, and Cosmetic Act of 1938 and amenments | thorough testing of drug, prood of safety and efficacy of drug |
Dietary Supplement Health and Education Act of 1994 | controls misleading industry claims |
Food and Drug Adminstration (FDA) | Agency of US department of health and human services in 1988 |