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UTSW Core II Autonom

Responses of Effector Organs to Autonomic Nerve Impulses

QuestionAnswer
eye radial muscle iris a1 - sympathetic contraction ++
eye sphincter muscle iris M3M2 - para contraction +++
eye ciliary muscle B2 - sympathetic relaxation +; M3M2 - para contraction +++
eye lacrimal glands a - sympathetic secretion +; M3M2 - para secretion +++
heart SA node B1 > B2 - sympathetic increase in HR ++; M2 >> M3 - para decrease in HR +++
heart atria B1 > B2 - sympathetic increase in contractility & conduction velocity ++; M2 >> M3 para decrease in contractility ++ & shortened action potential
heart AV node B1 > B2 - sympathetic increase in automataicity & conduction velocity ++; M2 >> M3 para decrease in conduction velocity; AV block +++
heart His-Purkinje system B1 > B2 symp. increase in automaticity & conducton velocity; M2 >> M3 para little effect
heart ventricle B1 > B2 symp increase in contractility, conduction velocity, automaticity & rate of idioventricular pacemakers +++; M2 >> M3 para slight decrease in contractility
arteries & arterioles - coronary a1a2B2 - symp constriction+; dilation++
arteries & arterioles - skin & mucosa a1a2 - symp constriction +++
arteries & arterioles - skeletal muscle a1B2 - symp constriction, dilation ++; ? - para dilation
arteries & arterioles - cerebral a1 - symp constriction (slight)
arteries & arterioles - pulmonary a1B2 - symp constriction+, dilation
arteries & arterioles - abdominal viscera a1B2 - symp constriction +++, dilation +
arteries & arterioles - salivary glands a1a2 - symp constriction +++; M3 - para dilation ++
arteries & arterioles - renal a1a2B1B2 - symp constriction ++, dilation ++
Veins a1a2B2 - symp constriction dilation
lung - tracheal & bronchial smooth muscle B2 - symp relaxation; M2 = M3 para contraction
lung - bronchial glands a1B2 - symp decrease secretion; increased secretionM3M2 - para stimulation
endothelium M3 - para activation of NO synthase
stomach - motility & tone a1a2B1B2 - symp decrease (usually); M2 = M3 - para increase +++
stomach - sphincters a1 - symp contraction (usually) +; M3M2 - para relaxation (usually) +
stomach - secretion a2 - symp inhibition; M3M2 - para stimulation ++
intestine - motility & tone a1a2B1B2 - symp decrease +; M3M2 - para increase +++
intestine - sphincters a1 - symp contraction +; M3M2 - para relaxation usually +
intestine - secretion a2 - symp inhibition; M3M2- para stimulation ++
Gallbladder & ducts B2 - symp relaxation +; M - para contraction +
kidney renin secretion a1B1 - symp decrease+; increase ++
Urinary bladder - detrusor B2 - symp relaxation +; M3 > M2 - para contraction +++
Urinary bladder - trigone & sphincter a1 - symp contraction ++; M3 > M2 - para relaxation ++
Ureter - motility & tone a1 - symp increase; M3 > M2 - para increase (?)
Uterus a1 - symp pregnant contraction; B2 - symp relaxation; M - para variable; B2 - symp non-pregnant relaxation
male sex organs a1 - symp ejaculation +++; M3 - para erection +++
skin - pilomotor muscles a1 - symp ?
skin - sweat glands a1 - symp localized secretion; M3M2 - para generalized secretion
spleen capsule a1 - symp contraction +++; B2 - symp relaxation +
adrenal medulla symp - secretion of NE & E; N M - para secondarily
skeletal muscle B2 - symp increased contractility, glycogenolysis; K+ uptake
liver a1B2 - symp glycogenolysis & gluconeogenesis
pancreas - acini a - symp decreased secretion +; M3M2 - para secretion ++
pancreas - islets (B cells) a2 - symp decreased secretion +++, B2 - symp increased secretion +
Fat cells a1B1B2B3 - symp lipolysis +++, a2 - symp inhibition of lipolysis
Salivary glands a1 - symp K+ & water secretion +; M3M2 - para K+ & water secretion +++
nasopharyngeal gland M3M2 - para secretion
Pineal glands B - symp melatonin synthesis
posterior pituitary B1 - ADH secretion
Autonomic nerve endings, sympathetic terminals - autoreceptor a2A > a2C - symp inhibition of NE release
Autonomic nerve endings, sympathetic terminals - heteroreceptor M2M4 - para inhibition of NE release
Autonomic nerve endings, parasympathetic terminals - autoreceptor M2M4 - para inhibition of Ach release
Autonomic nerve endings, parasympathetic terminals - heteroreceptor a2A > a2C - symp inhibition of Ach release
Created by: UTSW1
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