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Infectious Disease 1
| Category | generic | Brand | Indication | Activity against | Essential Knowledge |
|---|---|---|---|---|---|
| Beta-lactam antibiotic (natural penicillin) | penicillin V potassium (PO), penicillin G potassium (IV) | Pharyngitis, SSTI, syphilis (IV/IM) | Streptococcus pyogenes, Treponema pallidum (syphilis) | ||
| Beta-lactam antibiotic (aminopenicillin) | amoxicillin (PO) | Otitis media, pharyngitis | Streptococcus pneumoniae, Streptococcus pyogenes | ||
| Beta-lactam antibiotic and beta-lactamase inhibitor | amoxicillin and clavulanate (PO) | Augmentin, Augmentin XR | Otitis media, bacterial sinusitis | MSSA, Streptococcus pneumoniae, anaerobes, Enterobacteriacae | |
| Beta-lactam antibiotic and beta-lactamase inhibitor | ampicillin and sulbactam (IV) | Unasyn | DFI, IAI | MSSA, Streptococcus pneumoniae, anaerobes, Enterobacteriacae | |
| Beta-lactam antibiotic and beta-lactamase inhibitor | piperacillin and tazobactam (IV) | Zosyn | HAP, DFI, IAI | Pseudomonas aeruginosa, anaerobes | |
| Beta-lactam antibiotic (first generation cephalosporin) | cephalexin (PO) | Keflex | SSTI | MSSA, Streptococcus pyogenes | |
| Beta-lactam antibiotic (first generation cephalosporin) | cefazolin (IV) | Ancef | Antimicrobial prophylaxis in surgery, CRBSI, SSTI | MSSA, Streptococcus pyogenes | |
| Beta-lactam antibiotic (second generation cephalosporin) | cefuroxime (IV, PO) | IV: Zinacef, PO: Ceftin | Bacterial sinusitis | Streptococcus pneumoniae, Haemophilus influenzae | |
| Beta-lactam antibiotic (third generation cephalosporin) | cefdinir (PO) | Omnicef | Otitis media, bacterial sinusitis | Streptococcus pneumoniae, Haemophilus influenzae | |
| Beta-lactam antibiotic (third generation cephalosporin) | ceftriaxone (IV, IM) | Rocephin | Meningitis, CAP, pyelonephritis | Streptococcus pneumoniae, Enterobacteriaceae | |
| Beta-lactam antibiotic (fourth generation cephalosporin) | cefepime (IV) | Maxipime | Meningitis, VAP, HAP, pyelonephritis | Pseudomonas aeruginosa, Enterobacteriaceae | Key Side Effects: diarrhea, hypersensitivity reactions, seizures or encephalopathy with excessive doses |