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P&I ADRs
Pain and Inflammation Adverse Drug Reactions
| Question | Answer |
|---|---|
| aspirin | -salicylism (ototoxicity) -Reye's Syndrome -bleeding -renal dysfunction -GI upset, heartburn, nausea, gastric uler |
| ibuprofen | -some bleeding or thromboembolic events -renal dysfunction -GI upset, heartburn, nausea, gastric ulcer |
| celecoxib | -increased platelet aggregation -->MI and stroke risk -renal dysfunction -GI upset, heartburn, diarrhea, nausea, gastric ulcer |
| acetaminophen | -liver damage (can lead to OD) -hypertension (especially in women taking long-term) |
| tramadol | -respiratory depression (rare) -seizures, urinary retention -sedation, dizziness, headache, nausea, constipation |
| morphine | -respiratory depression, cough suppression, orthostatic hypotension, urinary retention -sedation, constipation (chronic use), nausea and vomiting (acute use) |
| buprenorphine, naloxone, suboxone | -abstinence syndrome -increased cardiac workload -respiratory depression, sedation, dizziness, lightheadedness, drowsiness, nausea, headache |
| naloxone | -ventricular arrhythmias -abstinence syndrome |
| prednisone | -immune suppression, insomnia, hunger, leukocytosis -bruising, bleeding, irritability, paper thin skin -adrenal suppression, hyperglycemia, myopathy, fat redistribution, osteoporosis |
Created by:
mbaldwin13
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