click below
click below
Normal Size Small Size show me how
P&I Action
Pain and Inflammation Pharmacologic Action
| Question | Answer |
|---|---|
| aspirin and ibuprofen | inhibits action of cyclooxygenase 1 and 2 |
| celecoxib | inhibits cyclooxygenase 2 only |
| acetaminophen | limited effect to CNS only |
| tramadol | binds to opioid receptors and blocks reuptake of serotonin and norepinephrine |
| morphine | binds with mu receptors at the opioid receptor sites |
| buprenorphine, naloxone, suboxone | blocks mu receptors and activates kappa receptors |
| naloxone | blocks opioid receptors |
| prednisone | mimics cortisol by inhibiting synthesis of prostaglandins |