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GI ADRs
| Question | Answer |
|---|---|
| cimetidine | -impotence, gynecomastia, reduced libido, erectile dysfunction -confusion, arrhythmias, agranulocytosis, aplastic anemia -increased pneumonia risk |
| omeprazole | -bone loss -headache, abdominal pain, nausea, vomiting, diarrhea -hypomagnesemia |
| sucralfate | constipation |
| ondansetron | -serotonin syndrome, torsade de pointes, SJS -headache, dizziness, constipation, diarrhea |
| dimenhydrinate | -sedation and drowsiness -dizziness -anticholinergic effects |
| metoclopramide | -sedation, extrapyramidal symptoms (tardive dyskinesia), restlessness -neuroleptic malignant syndrome -diarrhea |
| polyethylene glycol | -diarrhea, electrolyte imbalance, nausea, cramping, flatulence |
| docusate sodium | -diarrhea, abdominal cramps -throat irritation, cramps |
| diphenoxylate with atropine, loperamide | -cardiac arrest and arrhythmia -tolerance and dependency -excessive dose can mimc opioid OD -anticholinergic effects |
| sulfasalazine | -orange-yellow urine and skin -angioedema, hematologic disorders -SJS, photosensitivity, rash -nausea, fever, rash, headache |