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Chapter 14
Seizures
| Term | Definition |
|---|---|
| Epilepsy | A neurological disorder characterized by recurrent, unprovoked seizures caused by abnormal electrical activity in the brain. |
| Absence seizure | A type of generalized seizure characterized by brief episodes of staring or loss of awareness, typically lasting only a few seconds. |
| Tonic-clonic seizures | also known as grand mal seizures, are a type of generalized seizure that involves two phases: the tonic phase, where the body stiffens and muscles contract, and the clonic phase, characterized by rythmic shaking or jerking movements. |
| Tonic | Stiffening of the limbs |
| Clonic | Limbs and face begin to jerk |
| Status epilepticus seizure | Continuous tonic-clonic seizures that last longer than 5 minutes or recur before the end of the postictal period of the previous seizure. |
| Partial seizures | Also known as focal seizures, originate in a specific are of the brain and can be classified into two types: Simple partial seizures and complex partial seizures |
| carbamazepine (Tegretol) | First drug of choice for partial seizures |
| lamotrigine (Lamictal) | Firrst drug of choice for Tonic-Clonic seizures |
| ethosuximide (Zarontin) | First drug of choice for absence seizures |
| diazepam (Valium) | First drug of choice for status epilepticus |
| Stevens-johnson syndrome | a severe, potentially life-threatening skin condition characterized by widespread skin rash, blistering, and mucous membrane involvement. |
| Stomatitis | inflammation of the mucous membranes in the mouth, which can cause symptoms like soreness, swelling, and ulcers. |
| Erythema multiforme | a skin condition characterized by the sudden appearance or red, target-like lesions of spots on the skin, often triggered by infections, medications, or other factors |
| Trigeminal neuralgia | a chronic pain condition characterized by sudden, severe facial pain along the distribution of the trigeminal nerve. |
| Antiseizure agents | gabapentin (Neurontin) lamotrigine (Lamictal) levetiracetam (Keppra, Keppra XR) phenytoin (Dilantin) pregabalin (Lyrica) valproate (Depacon, Depakote) carbamazepine (Tegretol) |
| Barbiturate / antiseizure agent | phenobarbital (Sezaby) (Luminal) |
| gabapentin (Neurontin) class | Antiseizure agent |
| gabapentin (Neurontin) indication | seizure |
| lamotrigine (Lamictal) class | antiseizure agents |
| lamotrigine (Lamictal) indication | seizure |
| levetiracetam (Keppra, Keppra XR) class | antiseizure agent |
| levetiracetam (Keppra, Keppra XR) indication | seizure |
| phenytoin (Dilantin) class | Antiseizure agent |
| phenytoin (Dilantin) indication | seizure |
| pregabalin (Lyrica) class | Antiseizure agent |
| pregabalin (Lyrica) indication | seizures |
| valproate (Depacon, Depakote) class | antiseizure agents |
| valproate (Depacon, Depakote) indication | Seizures |
| phenobarbital (Sezaby) (Luminal) class | barbiturate / antiseizure agent |
| phenobarbital (Sezaby) (Luminal) indication | Seizures |
| carbamazepine (Tegretol) class | Antiseizure agent |
| carbamazepine (Tegretol) indication | seizures |