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ch. 12
aseptic techniques and sterile compounding
| Term | Definition |
|---|---|
| Anteroom | The room adjacent to the "clean room" used for donning all personal protective equipment (PPE) and wiping down all supplies that will be used in the compounding area |
| aseptic technique | The procedures used to eliminate the possibility of a drug becoming contaminated with microbes or particles |
| CSP | Compounded sterile preparation |
| Biological Safety Cabinet (BSC) | A vertical flow hood that should be used for making hazardous sterile preparations in the clean room |
| Compounding Aseptic Containment Isolator (CACI) | ISO Class 5 compounding area used hazardous drugs |
| Clean Room | In pharmacy, a contained and controlled environment in the pharmacy that has a low level of environmental pollutants (eg. dust, airborne microbes, aerosol particles, and chemical vapors); is used for preparing sterile medication products |
| Compounded Sterile Preparations (CSPs) | Preparations prepared in a sterile environment using non-sterile ingredients or devices that must be sterilized before administration |
| critical site | Any surface or area exposed to first air, which is exposed or at risk for touch, or direct air (ie, vial tops, open ampules, needle hubs, or injection ports) |
| Gauges | the size of needle openings |
| first air | air exiting the heap filter in a unidirecrtional |
| HEPA | high efficiency particulate air |
| hazardous drug | Any drug that has been proven to have dangerous effects during animal or human testing; it may cause cancer or may harm certain organs or pregnant women |
| hazardous waste | any waste that meets the resources conservation and recovery act criteria of ignitabilility |
| RCRA | Resources conservation and recovery act |
| Health Care-Associated Infection (HAI) | An infection that patients acquire during the course of receiving treatments for other conditions in an institutional setting |
| Horizontal Laminar Flow Hood | An environment for the preparation of compounded sterile preparations in which air originating from the back of the hood moves forward across the hood and into the room |
| Hyperailmentation | Parenteral nutrition for individuals who are unable to eat solids or liquids |
| infection control | Policies and procedures put in place to minimize the risk of spreading infections in hospitals or other health care facilities |
| Laminar Airflow Hood | An environment for the preparation of sterile products |
| Parenteral Medications | Medications that bypass the digestive system but are intended for systemic action; the term parenteral most commonly describes medications given by injection, such as intravenously or intramuscularly` |
| Peripheral Parenteral Nutrition (PPN) | Intravenous nutrition administered through veins on the periphery of the body rather than through a central vein or artery |
| Primary Engineering Control (PEC) | A device or zone that provides Class 5 environment for sterile compounding (ie, hoods) |
| Reconstituted | A substance that has had a diluent (eg. saline or sterile water) added to a powde |
| Standard Operating Procedures (SOPs) | Written guidelines and criteria that list specific steps for various competencies |
| Standard Precautions (Universal Precautions) | A set of standards that reduces the possibility of contamination and the risk of transmission of infectious disease; these standards are used throughout a health care facility, including to prepare medications |
| Sterile Preparation | A preparation that contains no living microoraganisms |
| Total Parenteral Nutrition (TPN) | Large volume intravenous nutrition administered through the central vein, which allows for a higher concentration of solutions |
| United States Pharmacopeia <797> (USP <797>) | National Formulary.standards; describes the guidelines, procedures, and compliance requirements for compounding sterile preparations; and sets the standards that apply to all settings in which sterile preparations are compounded |
| United States Pharmacopeia <800> (USP <800>) | "A new general chapter created to identify the requirements for receipt, storage, mixing, preparing, compounding, dispensing, and administration or hazardous drugs to protect the patient, health care personnel, and environment |
| Vertical Laminar Flow Hood | An environment for the preparation of chemotherapeutic and hazardous agents in which air originating from the roof of the hood moves downward (over the agent) and is captured in a vent on the floor of the hood |
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