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6aneslocal

Anestesicos Locales, Esteres, Amidas

QuestionAnswer
Anestesicos Locales Esteres, Amidas
Esteres Bloquean canales de Na+
Esteres Metabolito Toxico PABA
Unico Vasoconstrictor Cocaina
Grupo Aromatico Da liposubilidad
Grupo Ester Tipo de degradacion
Cadena Hidrocarbonada Liposolubilidad
Grupo Amino Hidrosolubilidad
Forma No Ionizada Difunde Rapido
Forma Ionizada Se queda en membrana
Sal estable y poco soluble en agua Clorhidratos
Esteres Anestesicos Locales Cocaina, Procaina, Cloroprocaina, Tetracaina, Proparacaina, Benzocaina
Metaboliza a Prilocaina Procaina
Es el Graneodin, dolores de garganta, oido, hemorroides Benzocaina
Anestesicos locales combinado con Adrenalina causan: Toxico, Necrosis Tisular y Gangrena
Aumentan la concentracion de anestesicos locales Benzodiacepinas
Si se usa un vasoconstrictor usar menor cantidad
Amidas Anestesicos Locales Lidocaina, Prilocaina, Bupivacaina, Dibucaina, Etidocaina, Cloroprocaina, Tetracaina, Ropivacaina
Primera eleccion infarto agudo al miocardio Lidocaina
Alergicos a esteres Lidocaina
Una potencia Procaina
Efecto Antiarritmico Lidocaina
Causa metahemoglobina Prilocaina
Tx. de Metahemoglobina Acido Ascorbico, Azul de Metileno
Hidroliza Rapido Cloroprocaina
CARDIOTOXICO Bupivacaina
Tx. Prurito Genital Dibucaina (muy toxico)
Mesoterapia por ser lipofilico Etidocaina
Gastroscopia, Anestesia Nariz Tetracaina
Epidural, Poco Bloqueo motor Ropivacaina
Baja Potencia 30-60 mins Procaina, cloroprocaina
Moderada Potencia 1-2 horas Mepivacaina, Lidocaina, Prilocaina
Alta Potencia 3-5 horas Bupivacaina, Tetracaina, Etidocaina
Created by: mildred
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