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Pharm exma 1
Review for pharmacology Exam 1
| Question | Answer |
|---|---|
| What is a drug that binds to and stimulates the activity of one or more receptors in the body. | An Agonist |
| What is a drug that binds to and inhibits the activity of one or more receptors in the body. | An Antagonist |
| First-pass effect is what? | The initial metabolism in the liver of a drug absorbed from the gastrointestinal tract before the drug reaches systemic circulation through the bloodstream. |
| Intraarterial | Within an artery (e.g., intraarterial injection). |
| Intraarticular | Within a joint (e.g., intraarticular injection). |
| Intrathecal | Within a sheath (e.g., the theca of the spinal cord, as in an intrathecal injection into the subarachnoid space). |
| The patent life for a drug is? | 17 years |
| Pharmaceutics is the study of how | various dosage forms influence the way in which the drug affects the body. |
| Pharmacokinetics is the study of | what the body does to the drug though the processes of absorption, distribution, metabolism, and excretion. |
| Pharmacodynamics is the study of what | the drug does to the body. |
| Pharmacotherapeutics (also called therapeutics) focuses on the | clinical use of drugs to prevent and treat diseases. It defines the principles of drug actions. |
| Enteral | Tablets, capsules, oral soluble wafers, pills, timed-release capsules, timed-release tablets, elixirs, suspensions, syrups, emulsions, solutions, lozenges or troches, rectal suppositories, sublingual or buccal tablets |
| Parenteral | Injectable forms, solutions, suspensions, emulsions, powders for reconstitution |
| Topical | Aerosols, ointments, creams, pastes, powders, solutions, foams, gels, transdermal patches, inhalers, rectal and vaginal suppositories |
| Would you crush drugs that have: SR, SA, CR, XL, or XT as part of their name | NO NEVER they are extended-release formulations |
| Metabolism is also referred to as | biotransformation |
| Cytochrome P-450 Enzymes | Metabolizes most drugs in the liver |
| Excretion is the elimination of drugs from the body what is the primary organ for this? | THE KIDNEYS!! |
| A drug’s onset of action is the time required for the drug to | elicit a therapeutic response. |
| A drug’s peak effect is the time required for a drug to reach its maximum | therapeutic response. |
| Grapefruit juice does what? | Decreases metabolism of drugs and increased effects |
| What is the antidote for acetaminophen | acetylcysteine |
| What is an antidote for Opiates, opioid drugs | naloxone |
Created by:
FutureNurse27
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