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MCPHS Patho Exam 2

MCPHS - Patho 2 Exam 2 (1)

QuestionAnswer
Two main returns to the heart? Inferior & Superior Venae Carvae
Arterial blood from heart to capillaries
Venous Blood from capillaries to Heart
Organs arranged In parallel
Organs and Lungs arranged Lungs are in Series with Organs
The Right & Left Pulmonary Artery comes from where? The Right Ventricle of Heart, carries deOx Blood to Lungs
Right & Left Pulmonary Veins come from where? Left Ventricle of Heart, Carries Ox Blood to Lungs
Right & Left Chambers are Separated by? Interventricular Septum
Blood from Right Ventricle goes to? Lungs
Blood from Left Ventricle goes thru Aorta to ? Organs
Blood from organs goes to? Right Atrium
Blood from Lungs goes to? Left Atrium
Force of Contraction Equation is? F = (Press Arteriol - Press Veinous) / Resistance Dia. of Vessels
Name of Heart Valves? Atrioventricular & Semilunar Valves (2 each)
Blood flow from Organs is determined by? Arterial Pressure & Changes in Vessel Diameter
Right & Left AV Valves AKA? Tri-cuspid (R) & Bi-Cuspid (L) Valves
When Atrial Press is Higher than Ventricular Pressure what happens? AV Valve Opens adn Ventricle fills
When Ventricle Press > Atrial Press? AV Closes & Ventricle contracts. Blood is prevented from backflow
SemiLunar Valves are located? B/w Ventricles and arteries
Heart wall is arranged in? Spial Arrangement so that heart twists when contracting
Endocardium ? Lines Inside of Heart and is part of Epithelium of Circulatory system
Myocardium is ? Bulk of Cardiac Muscle, the walls of heart..
Epicardium? External membrane of Heart. The coronary vescles are located in the Epicardium layer around heart
Heart walls are surrounded by? Pericardial Sac
Pericardial Inflammation is called? Pericarditis
Branching fibers of heart are connected by? Intercalated Discs
2 Types of Intercalated Discs? Desmosomes (mechanical connections) & Gap Junctions (Elec. Impulses)
Functional Syncytia means? muscle cells function as one unit
Cardiac Muscles are also Called? Cardiac Myocites
Coordination of Heart Contraction is known as? Excitation-Contraction Coupling
SA Node is located? Upper Right Atrial
Sympathetic Rate? Increases Rate (120 B/min)
Parasympathetic Rate is? Decreases Heart Rate (60-90 B/min)
Resting Heart Rate is Driven by? SA Node (70-80 B/min)
AV Node set rate ? AV Node 40 - 60 b/min
Purkinje AP's are? Purkinje AP set rate is 20 - 40 b/min
Pace Maker Conductivity is also Called? Dromotropy
Purkinje Conduction Rate is? Fastest at 4 m/sec causing fast contaction of ventricles
AV Node Conduction Rate is? Slowest, allowing for Ventricle fill time
What can speed up symathetic system of heart? Muscarinic Receptor Antagonists, Beta-Agonists, Catacholamines, HyperThyroidism
What can slow down Parasymapthetic system of heart? Muscarinic Receptor Agonists, Beta-Blockers, Hypoxia, Na & Ca Chann. Blkrs
Two types of Action Potentials ? Pacemaker & Non-pacemaker AP
Pacemaker AP's are from? SA & AV Nodes, Bundle of His, Purkinje fibers
Non-Pacemaker AP's are from? Atria & Ventricles, they have a true resting potential maintained by potassium
Duration of cardiac AP's? Around 500 ms
Phase 4 of SA Node? Distole (Resting Phase) Slow Na channels open "pacemaker current"
Phase 0 of SA Node? Depolarization Volt-Depen Ca Chn Open (L&T type) quick rise to zero w/ Ca Influx
Phase 3 of SA Node? Repolarization Volt-gated K+ Chn Open "Delayed Rectifier" Eflux of K+
Pacemaker Cells are? Never at Rest, always slowly depolarizing
How many phases in SA Node AP's? Phases: 4 (Diastole), 0 (Depolarization), 3 (Repolarization)
Phase 3 of SA Node AP's is also Called? Delayed Rectifier Current
What is phase 3 repolarization of SA Node caused by? Potassium Eflux
What is Phase 0 of SA Node caused by? Calcium Influx (Depolarization)
Phase 4 (first stage in SA Node AP) is also called? Distole (Resting) phase of Pacemaker currrent caused by Slow Sodium Channels Opening
# of Purkinje fiber AP phases? Phases: 0 (Depol), 1 (Early RePol), 2 (Plateau), 3 (RePol), 4 (Diastole)
Phase 0 of Purkinje AP ? FAST volt-Depnd Na+ Chn Open
Phase 1 of Purkinje AP? Early Repolarization Na+ Chn Close & Transient Outward K+ Chn Open (K+ Flows Out Rapidly)
Phase 2 of Purkinje AP? Plateau L-Type Ca++ Chn Open & K+ Rectifying Chns Open and K+ Flows Out
Phase 3 of Purkinje AP? Repolarization Ca++ Chn Close & K++ Flows Out Rapidly
Phase 4 of Purkinje AP? Distole Pacemaker Current
Phase 4 of Purkinje Resting Neg Potential Maintained by K+ Chns. Inward Rectifying
Ca++ Pump is dependent on? ATP
Na+ / Ca++ Exchanger Ratio is? Na/Ca (3:1)
Na+ / K+ ATPase Pump Ratio is? Na/K (3:2)
When are AP's Unexcitable? Absolute Refractory Period (ARP)
What is ERP? Effective Refractory Period just beyond the Abs Refract Period where WEAK DePol can occur, but does NOT Propagate
RRP is? Relative Refratory Period WEAK AP DOES Propagate, but more SLOWLY than usual
Where is ARP on Purkinje type curve? ARP (Phase 1 to 2) of plateau
Where is ERP? ERP is on end part of phase 2 plateau, but not right on the curve
Where is RRP? RRP is on the end of Phase 2 thru 3 ON Curve and down (shows backward dip at end of Phase 3)
What is a P wave? Atrial Depolarization
What is QRS Wave? Ventricle Depolarization
What is T Wave? Ventricle Repolarization
What is P-R Interval? Time from Atrial Repol to Spread of Impulse thru AV Node
What is QT Interval? Time from Ventricular DePol to RePol
What is ST Segment? End of Ventricular Depol & Begining of Ventricular Repol
Created by: MCPHS
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