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MCPHS Patho Exam 2
MCPHS - Patho 2 Exam 2 (1)
Question | Answer |
---|---|
Two main returns to the heart? | Inferior & Superior Venae Carvae |
Arterial | blood from heart to capillaries |
Venous | Blood from capillaries to Heart |
Organs arranged | In parallel |
Organs and Lungs arranged | Lungs are in Series with Organs |
The Right & Left Pulmonary Artery comes from where? | The Right Ventricle of Heart, carries deOx Blood to Lungs |
Right & Left Pulmonary Veins come from where? | Left Ventricle of Heart, Carries Ox Blood to Lungs |
Right & Left Chambers are Separated by? | Interventricular Septum |
Blood from Right Ventricle goes to? | Lungs |
Blood from Left Ventricle goes thru Aorta to ? | Organs |
Blood from organs goes to? | Right Atrium |
Blood from Lungs goes to? | Left Atrium |
Force of Contraction Equation is? | F = (Press Arteriol - Press Veinous) / Resistance Dia. of Vessels |
Name of Heart Valves? | Atrioventricular & Semilunar Valves (2 each) |
Blood flow from Organs is determined by? | Arterial Pressure & Changes in Vessel Diameter |
Right & Left AV Valves AKA? | Tri-cuspid (R) & Bi-Cuspid (L) Valves |
When Atrial Press is Higher than Ventricular Pressure what happens? | AV Valve Opens adn Ventricle fills |
When Ventricle Press > Atrial Press? | AV Closes & Ventricle contracts. Blood is prevented from backflow |
SemiLunar Valves are located? | B/w Ventricles and arteries |
Heart wall is arranged in? | Spial Arrangement so that heart twists when contracting |
Endocardium ? | Lines Inside of Heart and is part of Epithelium of Circulatory system |
Myocardium is ? | Bulk of Cardiac Muscle, the walls of heart.. |
Epicardium? | External membrane of Heart. The coronary vescles are located in the Epicardium layer around heart |
Heart walls are surrounded by? | Pericardial Sac |
Pericardial Inflammation is called? | Pericarditis |
Branching fibers of heart are connected by? | Intercalated Discs |
2 Types of Intercalated Discs? | Desmosomes (mechanical connections) & Gap Junctions (Elec. Impulses) |
Functional Syncytia means? | muscle cells function as one unit |
Cardiac Muscles are also Called? | Cardiac Myocites |
Coordination of Heart Contraction is known as? | Excitation-Contraction Coupling |
SA Node is located? | Upper Right Atrial |
Sympathetic Rate? | Increases Rate (120 B/min) |
Parasympathetic Rate is? | Decreases Heart Rate (60-90 B/min) |
Resting Heart Rate is Driven by? | SA Node (70-80 B/min) |
AV Node set rate ? | AV Node 40 - 60 b/min |
Purkinje AP's are? | Purkinje AP set rate is 20 - 40 b/min |
Pace Maker Conductivity is also Called? | Dromotropy |
Purkinje Conduction Rate is? | Fastest at 4 m/sec causing fast contaction of ventricles |
AV Node Conduction Rate is? | Slowest, allowing for Ventricle fill time |
What can speed up symathetic system of heart? | Muscarinic Receptor Antagonists, Beta-Agonists, Catacholamines, HyperThyroidism |
What can slow down Parasymapthetic system of heart? | Muscarinic Receptor Agonists, Beta-Blockers, Hypoxia, Na & Ca Chann. Blkrs |
Two types of Action Potentials ? | Pacemaker & Non-pacemaker AP |
Pacemaker AP's are from? | SA & AV Nodes, Bundle of His, Purkinje fibers |
Non-Pacemaker AP's are from? | Atria & Ventricles, they have a true resting potential maintained by potassium |
Duration of cardiac AP's? | Around 500 ms |
Phase 4 of SA Node? | Distole (Resting Phase) Slow Na channels open "pacemaker current" |
Phase 0 of SA Node? | Depolarization Volt-Depen Ca Chn Open (L&T type) quick rise to zero w/ Ca Influx |
Phase 3 of SA Node? | Repolarization Volt-gated K+ Chn Open "Delayed Rectifier" Eflux of K+ |
Pacemaker Cells are? | Never at Rest, always slowly depolarizing |
How many phases in SA Node AP's? | Phases: 4 (Diastole), 0 (Depolarization), 3 (Repolarization) |
Phase 3 of SA Node AP's is also Called? | Delayed Rectifier Current |
What is phase 3 repolarization of SA Node caused by? | Potassium Eflux |
What is Phase 0 of SA Node caused by? | Calcium Influx (Depolarization) |
Phase 4 (first stage in SA Node AP) is also called? | Distole (Resting) phase of Pacemaker currrent caused by Slow Sodium Channels Opening |
# of Purkinje fiber AP phases? | Phases: 0 (Depol), 1 (Early RePol), 2 (Plateau), 3 (RePol), 4 (Diastole) |
Phase 0 of Purkinje AP ? | FAST volt-Depnd Na+ Chn Open |
Phase 1 of Purkinje AP? | Early Repolarization Na+ Chn Close & Transient Outward K+ Chn Open (K+ Flows Out Rapidly) |
Phase 2 of Purkinje AP? | Plateau L-Type Ca++ Chn Open & K+ Rectifying Chns Open and K+ Flows Out |
Phase 3 of Purkinje AP? | Repolarization Ca++ Chn Close & K++ Flows Out Rapidly |
Phase 4 of Purkinje AP? | Distole Pacemaker Current |
Phase 4 of Purkinje Resting | Neg Potential Maintained by K+ Chns. Inward Rectifying |
Ca++ Pump is dependent on? | ATP |
Na+ / Ca++ Exchanger Ratio is? | Na/Ca (3:1) |
Na+ / K+ ATPase Pump Ratio is? | Na/K (3:2) |
When are AP's Unexcitable? | Absolute Refractory Period (ARP) |
What is ERP? | Effective Refractory Period just beyond the Abs Refract Period where WEAK DePol can occur, but does NOT Propagate |
RRP is? | Relative Refratory Period WEAK AP DOES Propagate, but more SLOWLY than usual |
Where is ARP on Purkinje type curve? | ARP (Phase 1 to 2) of plateau |
Where is ERP? | ERP is on end part of phase 2 plateau, but not right on the curve |
Where is RRP? | RRP is on the end of Phase 2 thru 3 ON Curve and down (shows backward dip at end of Phase 3) |
What is a P wave? | Atrial Depolarization |
What is QRS Wave? | Ventricle Depolarization |
What is T Wave? | Ventricle Repolarization |
What is P-R Interval? | Time from Atrial Repol to Spread of Impulse thru AV Node |
What is QT Interval? | Time from Ventricular DePol to RePol |
What is ST Segment? | End of Ventricular Depol & Begining of Ventricular Repol |