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TX of Skin Infection
Treatment of common infections of the skin
| Question | Answer |
|---|---|
| Animal Bite (Prophylaxis or early infection) | Amoxicillin/clavulanate 875/125 mg PO BID ALT: Doxycycline, 100mg BID |
| Animal Bite (established infection) | Ampicillin/sulbactam, 1.5-3.0 g IV q6h Clindamycin 600 – 900 mg IV q8h plus ciprofloxacin 400 mg IV q12h or cefoxitin, 2 g IV q2h |
| Bacillary angiomatosis | Erythromycin, 500 mg PO qid ALT: Doxycycline, 100mg BID |
| Herpes simplex (primary genital) | Acyclovir, 800mg PO 5xd for 7-10 days ALT: Famciclovir, 500 mg PO tid for 7 – 10 days or Famciclovir, 500 mg PO tid for 7-10 days |
| Herpes zoster (immunocompetent host > 50 yrs of age) | Acyclovir, 800mg PO 5xd for 7-10 days ALT: Famciclovir, 500 mg PO tid for 7 – 10 days or Famciclovir, 500 mg PO tid for 7-10 days |
| Cellulitis (staphylococcal or streptococcal) | Nafcillin or oxacillin, 2 g IV q4-6h ALT: Cefazolin, 1-2 g q8h or Ampicillin / sulbactam, 1.5-3.0 g IV q6h or Erythromycin 0.5 1.0 g IV q6h or Clindamycin 600 – 900 mg IV q8h |
| MRSA Skin Infection | Vancomycin, 1g IV q12h ALT: Linezolid, 600mg IV q12h |
| Necrotizing fasciitis (group A streptococcal) | Clindamycin 600 – 900 mg IV q6 – 8h Plus Penicillin G, 4 million units IV q4h ALT: Clindamycin 600 – 900 mg IV q6 – 8h Plus Cephlasporin (first or second generation) |
| Necrotizing fasciitis ( mixed aerobes and anerobes) | Ampicillin 2 g IV q4h plus Clindamycin 600 – 900 mg IV q6 – 8h Plus ciprofloxacin, 400 mg IV q6 – 8H ALT: Vancomycin, 1g IV q6h Plus Metronidazole, 500 mg IV q6h Plus Ciprofloxacin, 400 mg IV q6 – 8H |
| Gas Gangrene | Clindamycin 600 – 900 mg IV q6 – 8h Plus Penicillin G, 4 million units IV q4h ALT: Cefoxitin, 2g IV q6h |
Created by:
hm1bryan
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