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Ganglionic Blockers
| Question | Answer |
|---|---|
| Two main ganglionic blockers? Overall action? | Hexamethonium, mecamylamine; reduce autonomic tone based on TISSUE SPECIFICITY and prevent barreflex change |
| Effects in SANS? | arterioles and veins vasodilate and hypotension/decreased return AND anhidrosis (sweat glands) |
| Effects in PANS? | tachy, mydriasis, cycloplegia, urinary retention, xerostomia, constipation |
| Note these are the OPPOSITE of what the system would normally do, as the ganglionic blockers are there to stop the ganglionic procedures |