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Autonomics IV

Adrenergic Agonists

QuestionAnswer
What are the 3 categories of adrenergic agonists? Direct, mixed, indirect
What are the 2 types of direct? selective and passive
What is the response for direct if pt is pre-treated with resperine or guanethidine? For mixed? For indirect? NOT reduced; reduced; abolished (no rxn)
For Selective direct, what are the 4 drugs and which receptors do they act on for selective direct acting adrenergic agonists? phenylepherine- alpha 1 clonidine- alpha 2 dobutamine- Beta 1 terbutaline- Beta 2
For non-selective direct, 4 drugs and receptors they act on? oxymetazoline- alpha 1 and 2 isoproterenol- Beta 1 and 2 Epi- alpha 1, 2 and Beta 1, 2 NE- alpha 1, 2 and beta 1
For mixed, 1 drug and its receptors? Ephedrine- alpha 1, 2, beta 1, 2, and releasing agent
For Indirect, what are the 3 categories? Example from each? releasing agents- amphetamine and tyramine Uptake inhibitor- cocaine MAO/COMT Inhibitors- pargyline and entacapone
Rule for Epi at low doses concerning which receptor it likes? NE at low doses? Beta; alpha
Created by: cpeluso
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