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Autonomic III b

Muscarinic Receptor Antagonists

QuestionAnswer
What are the 4 main muscarinic receptor antagonists? atropine, Scopolamine, Ipratropium, Benztropine/Trihexyphenidyl
What is the use of Atropine? antispasmadic (M3), antisecretory (M1 and M3), AchE overdose management, antidiarrheal (M1), ophthamology (M3), and prevent vagal rxn
What is the use of Scopolamine? motion sickness, sedation, memory block (CNS)
What is the use of Ipratropium? Asthma, COPD --> NO CNS and NO change in mucus
What is the use of Benztropine and Trihexyphenidyl? CNS entry via lipid soluble; for Parkinsonism and antipsychotic sx remedy
Created by: cpeluso
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