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MCRT- Aersol Therapy
Key Terms
| Question | Answer |
|---|---|
| aerosol | suspension of solid or liquid particles in a gas |
| aerosol output | weight or mass of aerosol particles produced by nebulizer per unit time or volume |
| aging | (aerosol) the process in which aerosol particles change size due to evaporation or hygroscopic properties |
| atomizer | device that produces an aerosol suspension of liquid particles without using baffles to control particle size |
| baffle | surface in a nebulizer designed specifically to cause infection of large aerosol particles, causing either further fragmentation or removal from the suspension via condensation back into the reservoir |
| breath actuated nebulizer | aerosol device that is responsive to the patient’s inspiratory effort and reduces or eliminates aerosol generation during exhalation |
| breath enhanced nebulizer | nebulizers that entrain air through the nebulizer during inspiration |
| chloroflurocarbons (CFCs) | propellants such as freon that were once used to power MDIs |
| deposition | refers to the amount of medication that is deposited onto the airways |
| emitted dose | mass of drug leaving the mouthpiece of the nebulizer or inhaler as aerosol |
| fine particle fraction | the portion of the drug mass in particles that are small enough to reach the lower respiratory tract |
| geometric standard deviation (GSD) | the variability of particle sizes in an aerosol distribution set at one standard deviation above or below with the median |
| heterodisperse | referring to an aerosol consisting of particles of varying diameters in sizes |
| hydrofluoroalkane (HFA) | The new, more environmental friendly propellant for MDIs |
| hygroscopic | attracting or absorbing moisture from the air |
| inertial impaction | deposition of particles by collision with a surface; the primary mechanism for pulmonary deposition of particles over 5 mm in diameter |
| inhaled mass | the amount of drug inhaled |
| mass median aerodynamic diameter (MMAD) | method used to describe aerosol particle size |
| nebulizer | device that produces an aerosol suspension of what would particles in a gaseous medium using baffling to control particle size |
| propellant | something that propels, provides thrust, as a propellant in a metered dose inhaler |
| residual drug volume | medication that remains in a small volume nebulizer after the device is no longer producing mist |
| respirable mass | proportion of aerosol drug of the proper particle size to reach the lower respiratory tract |
| scintigraphy | the method used to measure the distribution of a drug utilizing radioactive tags |
| sedimentation | primary mechanism for deposition of particles 1 to 5 mm in diameter in the Central Airways, when particles slow and settle out of suspension |
| therapeutic index | difference between the minimum therapeutic and minimum toxic concentrations of a drug |
| volume median diameter | expresses average particle size for laser diffraction |
| monodisperse | referring to an aerosol in which particles are of uniform size |
Created by:
smiddleton
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