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MS Other

Other Information for Musculoskeletal

QuestionAnswer
methotrexate -teratogenic -use folic acid to prevent toxicity -delayed effects
etanercept contraindicated for malignancies
tofacitinib -interacts with grapefruit juice and St. John's Wort -can increase cholesterol
raloxifene -use with calcium and vitamin D
alendronate -cannot take if unable to sit/stand for 30 minutes
denosumab therapy will take years
teriparatide -contraindicated in Paget's disease and metastatic bone disorders
calcitonin-salmon -antibody formation considered in patients with initial response to Miacalcin injection who later stops responding -can lead to reduction in plasma lithium
calcium citrate -contraindicated in history of malignancy -contraindicated in history of kidney stones
colchicine -contraindicated in renal and hepatic impairment -fatal overdoses reported -can cause neuromuscular toxicity -not analgesic medication -avoid grapefruit juice
probenecid -may cause exacerbation of acute gouty attack -interacts with loop diuretics
allopurinol -no use in acute gout attacks -hepatotoxic -best to take with meal
Created by: mbaldwin13
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