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ch.19 chabner
review of chapter 19
Question | Answer |
---|---|
forming small nipple-like projections | papillary |
abnormal formation of cells | dysplastic |
localized growth of cells | carcinoma in situ |
densely packed;containing fibrous connective tissue | schirrhous |
patterns resembling small, microscopic sacs | alveolar |
small gland-type sacs | follicular |
lacking structures typical of mature cells | undifferentiated |
loss of differentiation of cells and reversion to a more primitive cell type | anaplasia |
extending beyond the normal tissue boundaries | infiltrative |
having the ability to enter and destroy surrounding tissue | invasive |
spreading to a secondary site | metastasis |
replication of cells;two identical cells are produced from a parent cell | mitosis |
cellular substance(ribonucleic acid) that is important in protein synthesis | RNA |
infectious agent that reproduces by entering a host cell and using the host's genetic material to make copies of itself | virus |
rays given off by the sun | ultraviolet radiation |
an agent (hydrocarbon,insecticide,hormone)that causes cancer | chemical carcinogen |
genetic material within the nucleus that controls replication and protein synthesis | DNA |
region of genetic material that causes cancer;found in tumor cells or viruses | oncogene |
change in the genetic material of a cell | mutation |
energy carried by a stream of particles | radiation |
characterized by redness,swelling, and heat | inflammatory |
tumors are large,soft, fleshy | medullary |
containing dead tissue | necrotic |
mushrooming pattern of growth | fungating |
characterized by large, open, exposed surfaces | ulcerating |
tumors from large,open sacs filled with fluid | cystic |
tumors resemble wart-like growths | verrucous |
growths are projections from a base (sessile & pedunculated) | polypoid |
removal of tumor and a margin of abnormal tissue for diagnosis and possible cure for small tumors | excisional biopsy |
removal of entire tumor with large area of surrounding tissue and lymph nodes | en bloc resection |
burning a lesion | electrocauterization |
destruction by high-frequency electric sparks | fulguration |
cutting into a tumor and removing a piece to establish diagnosis | incisional biopsy |
freezing a lesion | cryosurgery |
wide resection involving tumor, organ of origin, and surrounding tissue in the area of the hip | pelvic extenteration |
test for presence of a portion of human chorionic gonadotropin hormone (a marker for testicular cancer) | beta-HCG test |
incision of the abdomen to determine extent of disease | staging laparotomy |
protein marker test to detect ovarian cancer cells in blood | CA-125 |
visual examination of the abdominal cavity;peritoneoscopy | laparoscopy |
test for the presence of a hormone receptor on breast cancer cells | estrogen receptor assay |
removal and microscopic examination of bone marrow tissue | bone marrow biopsy |
aspiration of tissue for microscopic examination | needle biopsy |
blood test for the pressence of an antigen related to prostate cancer | PSA test |
blood test for carcinoembryonic antigen (marker for GI cancer) | CEA test |
cells are scraped off tissue and microscopically examined | exfoliative cytology |
staging tumor | assessing the extent of tumor spread |
T1N2MO | tumor is present with palpable regional lymph nodes and metastases |
tumor requires large doses of radiation to produce death of cells | radioresistant tumor |
used in treatment of tumors with radiation | linear accelerators |
study of the distribution and removal of drugs in the body over a period of time | pharmacokinetics |
study of tumors | oncology |
treatment using drugs | chemotherapy |
general ill malnutrition associated with chronic disease such as cancer | cachexia |
malignant tumor of fiber-producing cells | cystic tumor |
alveol/o | small sac |
cac/o | bad |
carcin/o | cancer,cancerous |
cauter/o | burn,heat |
chem/o | chemical drug |
cry/o | cold |
cyst/o | sac of fluid |
fibr/o | fibers |
follicul/o | small grandular sacs |
fung/i | fungus,mushroom |
medull/o | soft,inner part |
mucos/o | mucous membrane |
mut/a | genetic change |
mutagen/o | causing genetic change |
onc/o | tumor |
papill/o | nipple-like |
pharmac/o | chemical drug |
plas/o | formation |
ple/o | many,more |
polyp/o | polyp |
radi/o | rays,xrays |
sarc/o | flesh,connective tissue |
scirrh/o | hard |
xer/o | dry |
-blastoma | immature tumor |
-genesis | formation |
-oma | mass, tumor |
-plasia | formation, growth |
-plasm | formation, growth |
-suppression | to stop |
-therapy | treatment |
ana- | backward |
apo- | off,away |
brachy- | short |
epi- | upon |
meta- | beyond;change |
cancerous tumor composed of epethelial tissue | carcinoma |
cancerous tumor composed of connective tissue | sacrcoma |
retinoblastoma and polyposis coli syndrome are | inherited cancers |
the assessment of tumor's degree of maturity or microscopic differentiation is __________ of a tumor | grading |
assessment of a tumor's extent of spread within the body | staging |
what does TNM staging system stand for | tumor;node;metastasis |
the transformation of adult,differentiated tissue to differentiated tissue of another type is called | metaplasia |
the formation of new blood vessels is known as | angiogenesis |
destruction of tissue by electric sparks generated by a high-frequency current | fulguration |
removal of entire tumor and regional lymph nodes | en bloc resection |
cutting into a tumor and removing a piece to establish a diagnosis | incisional biopsy |
removal of tumor and margin of normal tissue for diagnosis and possible cure of small tumors | excisional biopsy |
freezing a lesion to kill tumors | cryosurgery |
burning a lesion to destroy tumor cells | electrocauterization |
wide resection involving removal of tumor,its organ of origin, and surrounding tissue in the body space | extenteration |
method of treating cancer using high-energy radiation | radiation therapy |
a tumor that requires large doses of radiation to kill cells | radioresistant |
if radiation can cause loss of tumor cells without serious damage to surrounding regions, the tumor is | radiosensitive |
tumor that can be completely eradicated by irradiation | radiocurable |
method of giving radiation in small,repeated doses | fractionation |
drug that increase the sensitivity of tumors to x-rays | radiosensitizers |
treatment of cancerous tumors with drugs | chemotherapy |
the study of the distribution and disappearance of drugs in the body is | pharmacokinetics |
the use of two or more drugs to kill tumor cells | combination of chemotherapy |
large electronic device that produces high energy x-ray beams for treatment of deep-seated tumors | linear accelerator |
alkylating agents,antimetabolites,hormones, antibiotics, and antimitotics are all types of | chemotherapeutic agents |
implantation of seeds of radioactive material directly into a tumor | brachytherapy |
unit of radiation equal to 100 rad | gray |
radiation applied to a tumor from a distant source | external beam radiation (teletherapy) |
highly focused,high energy radiation requiring a cyclotron machine is | proton therapy |
defined areas that are bombarded by radiation | fields |
ulceration of lining cells in the mouth caused by radiation to the jaw | oral mucositis |
drug treatment for breast cancer destroys epithelial cells in the stomach and causes a sensation leading to vomiting | nausea |
radiation to the lungs causes inflammation of the lungs | pneumonitis |
chemotherapy for ovarian cancer causes loss of hair on the head | alopecia |
bone marrow destruction with leukopenia,anemia, and thrombocytopenia | myelosuppression |
radiation to the lungs causes increase in connective tissue | fibrosis |
radiation of salivary glands causes dryness of the mouth | xerostomia |
method of treatment | modality |
assisting treatment | adjuvant therapy |
report or plan of steps taken in an experiment or disease case | protocol |
absence of all signs of disease | remission |
symptoms of disease return | relapse |
condition of damage to normal tissues;disease | morbidity |
treatment that uses the body's own defense mechanisms to fight tumor cells | biological therapy |
substances produced by normal cells that directly block tumor growth or stimulate the immune system | biological response modifiers |
a biological response modifier that is made by lymphocytes | interferon |
biological response modifiers that are made by mouse cells and are able to bind to tumor cells | monoclonal antibodies |
programmed cell death | apoptosis |
malnutrition marked by weakness nad emaciation; usually associated with later stages of cancer | cachexia |
drugs that promote tumor cells to differentiate (mature), stop growing and die | differentiating agents |
anticancer drugs designed to block the function of growth factors, their receptors, and signaling pathways in tumor cells | molecularly targeted drugs |
unit of DNA composed of sugar, phosphate, and base | nucleotide |