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Chapter 6 & 23

Narcotic drugs and substance use disorders

TermDefinition
Codine Most common opioid used in dentistry
Codine+Tylenol Tylenol 3, provides greater pain relief
Cocaine Abusers exhibit dilated pupils(mydriasis)
Morphine First natural opiate used for acute or severe pain
Oxycodone semi-synthetic opioid
Oxycodone + acetaminophen Percocet
Oxycodone + aspirin Percodan
Naloxone (Narcan) An opioid antagonist and used to treat opioid overdose
Agonists Refers to a substance that binds to and activates a receptor in the body
Mixed opioids AKA mixed agonist-antagonist opioids. Refers to a class of opiods that have both agonistic (activating) and antagonistic (blocking) effects on opioid receptors in the nervous system.
Antagonists Are substances that bind to receptors in the body but do not activate them. Instead, they block or inhibit the action of antagonists
Narcotics Original name for opiod drugs. greek: "inducing stupor or sleep"
Opioid agonists morphine, oxycodone, hydrocodone, codine, mathadone, Fentanyl
Opioid antagonists naloxone
Mixed opioids buprenorphine, tramadol
morphine (MS Contin, Kadian, Roxanol, Duramorph) classification Opioid
morphine (MS Contin, Kadian, Roxanol, Duramorph) indication Pain managment
oxycodone/acetaminophen (Percocet) classification Opioid
oxycodone/acetaminophen (Percocet) indication Pain management
hydrocodone/acetaminophen (Vicodin) classification Opioid
hydrocodone/acetaminophen (Vicodin) indication Pain managment
codeine (Codeine 15) classification Opioid
codeine (Codeine 15) indication Pain managment
methadone (Methadose) classification Opioid
methadone (Methadose) indication Treatment of opioid addicts
fentanyl (Duragesic, Actiq, Subsys, Sublimaze) Classification Opioid
fentanyl (Duragesic, Actiq, Subsys, Sublimaze) indication Pain managment
tramadol (Ultram, Conzip, Rybix) classification Opioid
tramadol (Ultram, Conzip, Rybix) indication Pain managment
buprenorphine (Buprenex) classification Opioid
buprenorphine (Buprenex) indication Pain managment
naloxone (Narcan) classification Opioid antagonists
naloxone (Narcan) indication Opioid overdose reversal
Abstinence syndrome A constellation of physiologic changes undergone by people who have become physically dependent on a drug or chemical who are abruptly deprived of that substance.
Addiction Addiction is a chronic, relapsing brain disease that is characterized by compulsive drug-seeking use despite complications or negative consequences
Substance use disorders occur when the recurrent use of alcohol and/or drugs causes clinically and functionally significant impairment.
Enabling The behavior of family or friends who associate with the addict that results in continued substance use disorder
Habituation Physiologic tolerance to or psychological dependence on a drug
Misuse Use of drug for a disease state in a way considered inapropriate
Physical/physiological dependence The state in which the drug is necessary for the continued functioning of certain body process.
Phsycologic dependence The state in which, following withdrawal of the drug, there are manifestations of emotional abnormalities and drug-seeking behavior.
Relapse The return to drug use after an attempt to stop
Tolerance With repeated dosing, the dose of a drug must be increased to obtain the same effect.
Withdrawal The constellation of symptoms, as specified in the DSM-5, that occurs when a physically dependent person stops taking the drug.
Mixed opioid: CNS depressants Ethyl alcohol
Opioid analgesic: agonists Heroin, meperidine
Benzodiazepine: sedative-hypnotics diazepam
CNS stimulants Cocaine, methamphetamine, caffine,nicotine
Withdrawal drugs Norepinephrine-dopamine reuptake inhibitor, bupropion, nicotine receptor partial agonists, varenicline
Psychedelics(Hallucinogens) Lysergic acid diethylamide(LSD), phencyclidine (PCP), acstacy, cannabis (Marijuana)
Ethyl alcohol classification mixed opioid
Ethyl alcohol indication Substacne abuse drug
Heroin classification opioid agonist
Heroin indication Substance abuse drug
meperidine(Demerol) classification Opioid agonist
meperidine(Demerol) indication Pain management
diazepam (Valium) classification Benzodiazepine
diazepam (Valium) indication Anxiety, muscle spasms, and seizures
Cocaine classification CNS stimulants
Cocaine indication Substance abuse drug (Anesthesia)
methamphetamine (Desoxyn) classification CNS stimulants
methamphetamine (Desoxyn) indication Substance abuse drug (ADHD)
Caffine (Stay awake) classification CNS stimulants
Caffine (Stay awake) indication Substance abuse drug
Nicotine (Nicroette, Nicoderm) classification CNS stimulants
Nicotine (Nicroette, Nicoderm) indication Substance abuse drug
bupropion (Wellbutrin SR) classification NDRI
bupropion (Wellbutrin SR) indication Withdrawal drugs: Smoking cessation/ Depression MDD & SAD/ ADHD
varenicline (Chantix) classification Nicotine receptor partial agonists
varenicline (Chantix) indication Withdrawal drugs: Smoking cessation
Lysergic acid diethylamide( LSD) classification Psychedelics (Hallucinogens)
Lysergic acid diethylamide( LSD) indication Substance abuse drugs
Phencyclidine (PCP) classification Psychedelics (Hallucinogens)
Phencyclidine (PCP) indication Substance abuse drugs
Ecstasy classification Psychedelics (Hallucinogens)
Ecstasy indication Substance abuse drugs
Cannabis (Marijuana) classification Psychedelics (Hallucinogens)
Cannabis (Marijuana) Substance abuse drugs
Created by: C.delaRocha
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